Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Creatinine (/kriˈætɪnɪn,-niːn/; from Ancient Greek: κρέας (kréas) 'flesh') is a breakdown product of creatine phosphate from muscle and protein metabolism. It is released at a constant rate by the body (depending on muscle mass).[3][4]
^ abMerck Index, 11th Edition, 2571
^"Creatinine, anhydrous - CAS 60-27-5". Scbt.com. Archived from the original on 2016-10-22. Retrieved 2016-10-21.
^"Creatinine tests - Mayo Clinic". www.mayoclinic.org. Archived from the original on 2022-06-05.
^Lewis SL, Bucher L, Heitkemper MM, Harding MM, Kwong J, Roberts D (September 2016). Medical-surgical nursing : assessment and management of clinical problems (10th ed.). St. Louis, Missouri: Elsevier Health Sciences. p. 1025. ISBN 978-0-323-37143-8. OCLC 228373703.
Creatinine (/kriˈætɪnɪn, -niːn/; from Ancient Greek: κρέας (kréas) 'flesh') is a breakdown product of creatine phosphate from muscle and protein metabolism...
through the kidney. The creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful...
In enzymology, a creatinine deaminase (EC 3.5.4.21) is an enzyme that catalyzes the chemical reaction creatinine + H2O ⇌ {\displaystyle \rightleftharpoons...
albumin in the sample against its concentration of creatinine is helpful. This is termed the albumin/creatinine ratio (ACR) and microalbuminuria is defined as...
called urea and electrolytes (U&E or "U and Es"), or urea, electrolytes, creatinine (UEC or EUC or CUE), and are often referred to as 'kidney function tests'...
the Bowman's capsule per unit time. Creatinine clearance is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure...
antihypertensive drugs. Hypertension. Severe depression, severe kidney failure (creatinine clearance <15 ml/min), as a precaution in the absence of currently available...
combination of factors such as decreased urine production or increased serum creatinine. Diagnosis of chronic failure is based on a glomerular filtration rate...
detect kidney problems. It is not considered as reliable as creatinine or BUN-to-creatinine ratio blood studies. BUN is an indication of kidney health...
in the urine may be compared to the creatinine level in a spot urine sample. This is termed the protein/creatinine ratio. The 2005 UK Chronic Kidney Disease...
catalyses the hydrolysis of creatinine to creatine, which can then be metabolised to urea and sarcosine by creatinase. creatinine + H2O ⇌ {\displaystyle \rightleftharpoons...
abnormally high levels of nitrogen-containing compounds (such as urea, creatinine, various body waste compounds, and other nitrogen-rich compounds) in the...
concentration of creatinine and symmetric dimethylarginine, but most Birman cats have higher concentrations of creatinine than SDMA. Creatinine is a creatine...
is often listed in medical literature under incorrect name "creatinine kinase". Creatinine is not a substrate or a product of the enzyme. Reference ranges...
The serum creatinine concentration is the most important blood test as it is used to estimate the function of the kidney, called the creatinine clearance...
function that develops within 7 days, as shown by an increase in serum creatinine or a decrease in urine output, or both. Causes of AKI are classified as...
blood of amino acid and protein metabolism end products, such as urea and creatinine, which would be normally excreted in the urine. Uremic syndrome can be...
reaction is a colorimetric method used in clinical chemistry to determine creatinine levels in blood and urine. In 1886, Max Jaffe (1841–1911) wrote about...
κρέας (kreas). In 1928, creatine was shown to exist in equilibrium with creatinine. Studies in the 1920s showed that consumption of large amounts of creatine...
people with creatinine clearance rates equal to or less than 30 mL/minute. A half-life of 22–50 hours has been reported for people with creatinine clearances...
(hyperkalemia). Can compete with creatinine for secretion into the renal tubule. This can cause an artificial rise in the serum creatinine. Use in EHEC infections...
potassium, chloride, bicarbonate, blood urea nitrogen (BUN), magnesium, creatinine, glucose, and sometimes calcium. Tests that focus on cholesterol levels...
blood test. A decreased creatinine clearance indicates poor kidney function. In interventional radiology, a patient's creatinine clearance levels are all...
studies have found cystatin C to be better in this regard than serum creatinine or creatinine-based GFR equations. Because the association of cystatin C with...
unilateral significant renal artery stenosis (RAS). An early rise in serum creatinine above baseline is expected after initiation of therapy with Ramipril,...
derived from the serum creatinine and is proportional to 1/creatinine, i.e. it is a reciprocal relationship; the higher the creatinine, the lower the GFR...
reasonably constant level in the plasma.: 228 In the United States, creatinine clearance is more widely used to estimate GFR. A 2017 systematic review...