Cortisone acetate (brand names Adreson, Cortison, Cortisone, Cortisone Acetate, Cortone, Cortistab, Cortisyl, others) is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed (under prescription) in many countries throughout the world, including in the United States, the United Kingdom, and various other European countries.[1][2][3] It is the C21 acetate ester of cortisone,[1][2] and acts as a prodrug of cortisone in the body.[4]
^ abElks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 317–. ISBN 978-1-4757-2085-3.
^ abIndex Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 276–. ISBN 978-3-88763-075-1.
^Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 85–. ISBN 978-94-011-4439-1.
^Løvås K, Husebye ES (December 2003). "Replacement therapy in Addison's disease". Expert Opinion on Pharmacotherapy. 4 (12): 2145–2149. doi:10.1517/14656566.4.12.2145. PMID 14640913. S2CID 37628998.
Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug...
second polymorph was found with more suitable compressive properties. Cortisoneacetate exists in at least five different polymorphs, four of which are unstable...
use (as the acetate ester) in 1954. It was the first synthetic corticosteroid to be marketed, and followed the introduction of cortisone in 1948 and hydrocortisone...
biologically inert cortisone to biologically active cortisol 11-beta HSD2 uses the cofactor NAD+ to convert cortisol to cortisone Overall, the net effect...
Hydrocortisone is metabolized by 11β-hydroxysteroid dehydrogenases (11β-HSDs) into cortisone, an inactive metabolite. It is additionally 5α-, 5β-, and 3α-reduced into...
Hydrocortisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. The acetate group helps to protect the hydrocortisone molecule...
synthetic pregnane corticosteroid and derivative of cortisone and is also known as δ1-cortisone or 1,2-dehydrocortisone or as 17α,21-dihydroxypregna-1...
to all steroids in that group. Hydrocortisone, hydrocortisone acetate, cortisoneacetate, tixocortol pivalate, prednisolone, methylprednisolone, and prednisone...
Trenbolone acetate, sold under brand names such as Finajet and Finaplix among others, is an androgen and anabolic steroid (AAS) medication which is used...
Prednisolone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of prednisolone. Prednisolone acetate is...
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically...
Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency contraception (birth control) and uterine fibroids...
Megestrol acetate (MGA), sold under the brand name Megace among others, is a progestin medication which is used mainly as an appetite stimulant to treat...
also been reported starting from a variety of steroids. For the example, cortisone can be simultaneously deoxygenated at the C-17 and C-21 position by treatment...
intraocular pressure, and eye infection caused by fungus. Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product...
Winter CA (1958). "16-Methylated steroids. II. 16α-Methyl analogs of cortisone, a new group of anti-inflammatory steroids. 9α-Halo derivatives". Journal...
week until replacement is reached. Then change to oral hydrocortisone or cortisone as a single morning dose, and gradually decrease by 2.5 mg each week....
in 2 mg, 4 mg, 8 mg, 16 mg or 32 mg strengths. Both methylprednisolone acetate (Depo-Medrol) and methylprednisolone succinate (Solu-Medrol) are approved...
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