Convection-enhanced delivery (CED) is method of drug delivery in which drug is delivered into using bulk flow rather than conventional diffusion into the brain. This is done by utilizing catheters inserted into the target region of the brain and utilizing pressure to deliver the therapeutic to a target region. CED has been used to delivery drugs to the central nervous system (CNS) for diseases such as cancer, epilepsy, and Parkinson's disease.[1][2][3] CED has been used to deliver drugs to the CNS for its ability to bypass the blood–brain barrier (BBB) and target specific regions for targeted treatment, but current techniques using CED have failed to progress past clinical trials due to a variety of physical limitations associated with CED itself.
^Jahangiri, Arman; Chin, Aaron T.; Flanigan, Patrick M.; Chen, Rebecca; Bankiewicz, Krystof; Aghi, Manish K. (January 2017). "Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies". Journal of Neurosurgery. 126 (1): 191–200. doi:10.3171/2016.1.jns151591. ISSN 0022-3085. PMC 5571827. PMID 27035164.
^Rogawski, Michael A. (April 2009). "Convection-enhanced delivery in the treatment of epilepsy". Neurotherapeutics. 6 (2): 344–351. doi:10.1016/j.nurt.2009.01.017. ISSN 1933-7213. PMC 2753495. PMID 19332329.
^Lam, Miu Fei; Thomas, Meghan G.; Lind, Christopher R.P. (September 2011). "Neurosurgical convection-enhanced delivery of treatments for Parkinson's disease". Journal of Clinical Neuroscience. 18 (9): 1163–1167. doi:10.1016/j.jocn.2011.01.012. ISSN 0967-5868. PMID 21745745. S2CID 24522456.
and 24 Related for: Convection enhanced delivery information
Convection-enhanceddelivery (CED) is method of drug delivery in which drug is delivered into using bulk flow rather than conventional diffusion into...
economic development Conjugate eye deviation Convectionenhanceddelivery, an experimental drug delivery method Course and Exam Description, a requirement...
each administration. This has been attempted with DIPG tumours. Convection-enhanceddelivery: Chemotherapy is delivered to the tumour by a surgically implanted...
procedures are invasive and can pose additional risk to the patient. Convectionenhanceddelivery uses an intracranial catheter to deliver drug through the interstitial...
1016/S0040-4039(01)92445-1. "John D. Heiss et al- Image Guided Convection-EnhancedDelivery of Muscimol to the Primate Brain". vdocuments.site/. Retrieved...
classified into various mechanisms, such as thermal conduction, thermal convection, thermal radiation, and transfer of energy by phase changes. Engineers...
"Regression of Recurrent Spinal Cord High-Grade Glioma After Convection-EnhancedDelivery of Nimustine Hydrochloride: Case Reports and Literature Review"...
healthcare delivery system in Illinois, US Enshi Xujiaping Airport (IATA code), China Tundra Enets language (ISO 639-3 code: enh) Enhanced, a convective outlook...
chimney – is a way of improving the natural ventilation of buildings by using convection of air heated by passive solar energy. A simple description of a solar...
and takhtabush-like arrangements (see sections on night flushing and convection, below).: Ch. 6 The construction of a windcatcher depends on the prevailing...
Bulk motion, or bulk flow, is the characteristic of advection. The term convection is used to describe the combination of both transport phenomena. If a...
tends to rise and transfer heat upward. This is the process of convection. Convection comes to equilibrium when a parcel of air at a given altitude has...
exchanger device that facilitates evaporation by utilizing conductive and convective heat transfer, which provides the necessary thermal energy for phase transition...
heat transfer called thermomagnetic convection. This form of heat transfer can be useful when conventional convection heat transfer is inadequate; e.g....
the fundamental mechanisms of heat transfer, along with conduction and convection. The primary method by which the Sun transfers heat to the Earth is thermal...
human body dissipates heat through perspiration and its evaporation. Heat convection, to the surrounding air, and thermal radiation are the primary modes of...
David P.; Senior, Catherine A. (2019). "Enhanced future changes in wet and dry extremes over Africa at convection-permitting scale". Nature Communications...
The air passes through the ceramic core by the natural process of air convection, and is then cooled using heat transfer plates and released. TSS is not...
heat transfer, especially if allowed to circulate by natural convection or forced convection through a heat exchanger. Liquid filling can be removed for...
efficient hearing aid, microphone, headphone, or recording studio to enhancing the sound quality of an orchestra hall. Acoustical engineering also deals...
a single environment, better coordination and development of designs, enhanced clash avoidance and detection, and improved time and cost decision-making...
referred to as "microgravity", the lack of sedimentation, buoyancy, or convective flows in fluids results in a more quiescent cellular and intercellular...
refrigerant. Air is a common form of a coolant. Air cooling uses either convective airflow (passive cooling), or a forced circulation using fans. Hydrogen...
and an enhanced risk was added for northeast Oklahoma northeastward through southeastern Kansas into western Missouri. At 16:30 UTC, the enhanced risk was...
Global Information