The complement fixation test is an immunological medical test that can be used to detect the presence of either specific antibody or specific antigen in a patient's serum, based on whether complement fixation occurs. It was widely used to diagnose infections, particularly with microbes that are not easily detected by culture methods, and in rheumatic diseases. However, in clinical diagnostics labs it has been largely superseded by other serological methods such as ELISA and by DNA-based methods of pathogen detection, particularly PCR.
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cascade of further cleavages. The end result of this complement activation or complementfixation cascade is stimulation of phagocytes to clear foreign...
Advancement of Science in Berlin-Dahlem (1913). Wassermann developed a complementfixationtest for the diagnosis of syphilis in 1906, just one year after the...
fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests...
agglutination test. HLA types are originally determined with the complementfixationtest. Newer procedures include the latex fixationtest and various...
direct fluorescent antibody (DFA), and serological methods (e.g. complementfixationtest). The bacteria can be recovered from the person only during the...
special forces unit of the Indian Navy Micro Complementfixationtest, a high-sensitivity immunological medical test Muskegon Correctional Facility, a state...
antibody–reaction has taken place in a test, other methods are needed to confirm this. Older methods included complementfixationtests, hemagglutination inhibition...
immunofluorescence, ELISA, Immunoblotting (Western blot), and Complementfixationtest are methods of identifying different kinds of parasites by detecting...
as test subjects, Canada used serological tests such as complementfixationtests to detect trypanosomes, and have been very successful. Other tests used...
a Social Problem in England. August von Wassermann develops a complementfixationtest for the diagnosis of syphilis. Walther Nernst presents a formulation...
precipitation, complement-fixation, and fluorescent antibodies and more recently chemiluminescence. In microbiology, serologic tests are used to determine...
existence of different strains using antigen-antibody interaction (complementfixationtest) in 1944. She observed that different strains had varying degree...
involved dated technology, for example immunodiffusion (ID) or complementfixationtests (CFT), or state-of-the-art technology including radioimmunoassay...
action of complement. These studies became the basis for complement-fixationtesting methods that enabled the development of serological tests for syphilis...
can be made by complementfixationtests. As of 2012[update], commercial blood tests included ELISA and an Indirect immunofluorescence test, but these have...
the positive test. Many traditional serological tests such as hemagglutination or complementfixation employ this principle. Such tests can typically...
HI (hemagglutination inhibition), NT (neutralization test), and CF (complementfixationtest) tests and in-house-enzyme linked immunosorbent assay for total...
serologic tests have been employed for the diagnosis of paracoccidioidomycosis. Double diffusion in agar gel and complementfixationtest, are amongst...
Antibody titers can also be measured with complementfixationtests, hemagglutination assays, and neutralization tests. In vaccinated people, antibody-based...
fourfold or greater difference in antibody based tests. These tests include ELISAs and complementfixationtests. Orbiviruses listed by serogroup Lebombo virus...
1990s, the only tests for California serogroup virus infections performed by most state diagnostic laboratories were complement-fixationtest and hemagglutination...
respiratory signs. Bacterial culture, immunofluorescent antibody testing (IFAT), complementfixationtest and haemagglutination can all be used to confirm the diagnosis...
to these antigens within the kidney could cause inflammation and complementfixation, resulting in kidney damage. Presence of high DNA-binding and low...
antibodies on different cells, causing agglutination. Complementfixation assay. The complementfixationtest was modified to assay Antiserum mediated RBC lysis...