Cold abscess refers to an abscess that lacks the intense inflammation usually associated with infection. This may be associated with infections due to bacteria like Mycobacterium tuberculosis, the cause of tuberculosis,[1] and fungi like those from the genus Blastomyces, which cause blastomycosis,[2] that do not tend to stimulate acute inflammation. Alternatively, cold abscesses are typical in persons with hyperimmunoglobulin E syndrome, even when infected with an organism like Staphylococcus aureus that causes abscesses with inflammation in others.[3]
Signs of acute inflammation are absent, so the abscess is not hot and red as in a typical abscess filled with pus. Cold abscesses are generally painless cysts that may be subcutaneous, ocular, or in deep tissue such as the spine.[4][5]
^Garg, RK; Somvanshi, DS (2011). "Spinal tuberculosis: A review". The Journal of Spinal Cord Medicine. 34 (5): 440–54. doi:10.1179/2045772311Y.0000000023. PMC 3184481. PMID 22118251.
^Ferri, Fred (2015). "Blastomycosis". Ferri's Clinical Advisor. Philadelphia: Mosby (Elsevier). pp. 198.e2–198.e4. ISBN 9780323083751.
^Holland, SM; DeLeo, FR; Elloumi, HZ; Hsu, AP; et al. (18 October 2007). "Mutations in the hyper-IgE syndrome". The New England Journal of Medicine. 357 (16): 1608–19. doi:10.1056/NEJMoa073687. PMID 17881745.
^Ansari, S; Amanullah, MF; Ahmad, K; Rauniyar, RK (July 2013). "Pott's spine: Diagnostic imaging modalities and technology advancements". North American Journal of Medical Sciences. 5 (7): 404–11. doi:10.4103/1947-2714.115775. PMC 3759066. PMID 24020048.
^Madge, SN; Prabhakaran, VC; Shome, D; Kim, U; et al. (2008). "Orbital tuberculosis: A review of the literature". Orbit. 27 (4). Amsterdam, Netherlands: 267–77. doi:10.1080/01676830802225152. PMID 18716964. S2CID 22033701.
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