Gene that is central to the circadian oscillator of angiosperms
Circadian Clock Associated 1
Identifiers
Organism
A. thaliana
Symbol
CCA1
RefSeq (mRNA)
NM_180129.3
RefSeq (Prot)
NC_003071.7
Other data
Chromosome
2: 19.25 - 19.25 Mb
Circadian Clock Associated 1 (CCA1) is a gene that is central to the circadian oscillator of angiosperms. It was first identified in Arabidopsis thaliana in 1993. CCA1 interacts with LHY and TOC1 to form the core of the oscillator system. CCA1 expression peaks at dawn. Loss of CCA1 function leads to a shortened period in the expression of many other genes.[1]
^Green RM, Tobin EM (March 1999). "Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression". Proceedings of the National Academy of Sciences of the United States of America. 96 (7): 4176–4179. Bibcode:1999PNAS...96.4176G. doi:10.1073/pnas.96.7.4176. PMC 22440. PMID 10097183.
and 24 Related for: Circadian Clock Associated 1 information
CircadianClockAssociated1 (CCA1) is a gene that is central to the circadian oscillator of angiosperms. It was first identified in Arabidopsis thaliana...
A circadianclock, or circadian oscillator, also known as one’s internal alarm clock is a biochemical oscillator that cycles with a stable phase and is...
the environment (is entrained by the environment). Circadian rhythms are regulated by a circadianclock whose primary function is to rhythmically co-ordinate...
These biological clocks control processes that fluctuate daily (e.g., body temperature, alertness, hormone secretion), generating circadian rhythms. Among...
genes in the Arabidopsis repressilator. The EE may be bound by CircadianClockAssociated1 (CCA1) and Late Elongated Hypocotyl (LHY) proteins to suppress...
by shift work and circadian rhythm sleep disorders. When travelling across a number of time zones, a person's body clock (circadian rhythm) will be out...
(see Circadian rhythm) in mammals are sensitive to temperature pulses and will experience resetting of the circadianclock phase and associated genetic...
sleep–wake phase disorder, is the delaying of a person's circadian rhythm (biological clock) compared to those of societal norms. The disorder affects...
CLOCK (from circadian locomotor output cycles kaput) is a gene encoding a basic helix-loop-helix-PAS transcription factor that is known to affect both...
There are candidate genes (called CLOCK genes) that exist in most cells in the body and brain, referred to as the circadian system that regulate physiological...
Two transcription factors, CircadianClockAssociated1 (CCA1) and Late Elongated Hypocotyl (LHY), repress genes associated with evening expression like...
Chronodisruption is a concept in the field of circadian biology that refers to the disturbance or alteration of the body's natural biological rhythms...
function of the circadianclock. ELF3 is one of the three components that make up the Evening Complex (EC) within the plant circadianclock, in which all...
feedback loops that generate circadian rhythm in mammals. The previously-characterized CK1ε isoform was first implicated as a clock gene when its Drosophila...
and mammal-like (Type II). CRY1 is a circadian photoreceptor whereas CRY2 is a clock repressor which represses Clock/Cycle (Bmal1) complex in insects and...
mammalian circadianclock (PER1, PER2). CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (activating...
mechanisms of circadian pacemakers. She is known for her extensive studies of photic and non-photic effects on the mammalian circadianclocks. Notably, Meijer...
operation of the cyanobacterial circadianclock. Discovery of the Kai genes marked the first-ever identification of a circadian oscillator in a prokaryotic...
explaining circadian rhythms in behavior and physiology. Widely conserved across species, the TTFL is auto-regulatory, in which transcription of clock genes...
positionally cloned the Drosophila Clock gene. In his laboratory at Northwestern, he discovered a conserved mechanism for circadian control of sleep-wake cycle...
Translation Negative Feedback Loop for circadianclocks in 1990. In 1998, they discovered the cycle gene, clock gene, and cryptochrome photoreceptor in...
disorder with diurnal mood variation symptoms. The circadian or clock system consists of multiple cellular clocks present in organs and tissues, and it plays...