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Schematic image showing a chylomicron
Chylomicrons (from the Greek χυλός, chylos, meaning juice (of plants or animals), and micron, meaning small),[1] also known as ultra low-density lipoproteins (ULDL), are lipoprotein particles that consist of triglycerides (85–92%), phospholipids (6–12%), cholesterol (1–3%), and proteins (1–2%). They transport dietary lipids, such as fats and cholesterol, from the intestines to other locations in the body, within the water-based solution of the bloodstream.[2] ULDLs are one of the five major groups lipoproteins are divided into based on their density. A protein specific to chylomicrons is ApoB48.
There is an inverse relationship in the density and size of lipoprotein particles: fats have a lower density than water or smaller protein molecules, and the larger particles have a higher ratio of internal fat molecules with respect to the outer emulsifying protein molecules in the shell. ULDLs, if in the region of 1,000 nm or more, are the only lipoprotein particles that can be seen using a light microscope, at maximum magnification. All the other classes are submicroscopic.
^"Definition of CHYLOMICRONS". www.merriam-webster.com. Retrieved 2024-04-26.
^Gofman, John W.; Jones, Hardin B.; Lindgren, Frank T.; Lyon, Thomas P.; Elliott, Harold A.; Strisower, Beverly (1950). "Blood Lipids and Human Atherosclerosis" (PDF). Circulation. 2 (2): 161–178. doi:10.1161/01.cir.2.2.161. PMID 15427204. S2CID 402420.
Chylomicrons (from the Greek χυλός, chylos, meaning juice (of plants or animals), and micron, meaning small), also known as ultra low-density lipoproteins...
lipid composition, and apolipoprotein content: HDL, LDL, IDL, VLDL and chylomicrons. Subgroups of these plasma particles are primary drivers or modulators...
phospholipids, cholesterol ester, and apolipoprotein B48 to form chylomicrons. These chylomicrons then pass into the lacteals, forming a milky substance known...
Chylomicron retention disease is a disorder of fat absorption. It is associated with SAR1B. Mutations in SAR1B prevent the release of chylomicrons in the...
cardiovascular disease. Apolipoprotein B is the primary apolipoprotein of chylomicrons, VLDL, Lp(a), IDL, and LDL particles (LDL—commonly known as "bad cholesterol"...
lipoprotein lipase (LPL) or altered apolipoprotein C2, resulting in elevated chylomicrons, the particles that transfer fatty acids from the digestive tract to...
phospholipids and proteins, forming a large transporter particle called chylomicron. The chylomicron enters a lymphatic capillary, then it is transported into the...
velocity gradients which push blood elements such as cholesterol or chylomicron bodies to the endothelium. These deposit onto the arterial walls which...
and protein (protein coat) into a compound called a chylomicron. From within the cell, the chylomicron is released into a lymphatic capillary called a lacteal...
also in other tissues, partially digests the chylomicrons into free fatty acids, glycerol and chylomicron remnants. The fatty acids are absorbed by the...
lipoproteins in the blood. In order of increasing density, they are chylomicrons, very-low-density lipoprotein (VLDL), intermediate-density lipoprotein...
from the digestive system (beginning in the lacteals) to the blood via chylomicrons. Bacteria may enter the lymph channels and be transported to lymph nodes...
lipoproteins in smaller amounts. Apolipoprotein A-IV (apoA4) is present in chylomicrons, very-low-density lipoproteins (VLDL), and HDL. It is thought to act...
that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and...
present as part of several classes of lipoprotein particles, including chylomicron remnants, VLDL, IDL, and some HDL. APOE interacts significantly with...
apolipoproteins B-48 and B-100, which are used in the synthesis and exportation of chylomicrons and VLDL respectively. It is not to be confused with familial dysbetalipoproteinemia...
malformation, a narrowing of the skull which puts pressure on the cerebellum Chylomicron, lipoprotein with extremely low density Contingency management, a type...
APOE may refer to: Apolipoprotein E, a main apoprotein of the chylomicron, also studied for its involvement in Alzheimer's disease risk Professional Oklahoma...
such into chylomicrons or first converted to retinal and then retinol, bound to RBP2. After a meal, roughly two-thirds of the chylomicrons are taken up...
either hydrolyzed by phospholipases or enter the lymph incorporated into chylomicrons. In humans, choline is transported as a free molecule in blood. Choline–containing...
The receptor also recognizes apolipoprotein E (ApoE) which is found in chylomicron remnants and IDL. In humans, the LDL receptor protein is encoded by the...
liver receives many lipids from the systemic circulation and metabolizes chylomicron remnants. It also synthesizes cholesterol from acetate and further synthesizes...
fragments and packaged together with cholesterol and proteins to form chylomicrons. These are excreted from the cells and collected by the lymph system...
medicines) are absorbed to the lymph and move in it enveloped inside chylomicrons. They move via the thoracic duct of the lymphatic system and finally...
alpha-tocopherol, are absorbed from the intestinal lumen, incorporated into chylomicrons, and secreted into the portal vein, leading to the liver. Absorption...
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