Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in the pancreas. In humans, chromogranin A protein is encoded by the CHGA gene.[5]
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021194 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Helman LJ, Ahn TG, Levine MA, Allison A, Cohen PS, Cooper MJ, et al. (August 1988). "Molecular cloning and primary structure of human chromogranin A (secretory protein I) cDNA". The Journal of Biological Chemistry. 263 (23): 11559–63. doi:10.1016/S0021-9258(18)37995-X. PMID 3403545.
ChromograninA or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it...
Granin (chromogranin and secretogranin) is a protein family of regulated secretory proteins ubiquitously found in the cores of amine and peptide hormone...
identify with any current technology. Markers of the condition such as chromogranin-A are imperfect indicators of disease progression. The incidence of neuroendocrine...
notable is ChromograninA. In comparison to the specificity of elevated catecholamines in the pheochromocytoma patient, chromograninA is a non-specific...
arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass. These cancerous cells have the...
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B12. Those affected often have a gradual onset....
terminal Synaptic cleft Dendrite A neurotransmitter is a signaling molecule secreted by a neuron to affect another cell across a synapse. The cell receiving...
of products such as pancreatic polypeptide (PPoma), chromograninA, and neurotensin do not cause a clinical syndrome, although blood levels may be elevated...
II (chromogranin C), is a protein which in humans is encoded by the SCG2 gene. The protein encoded by this gene is a member of the chromogranin/secretogranin...
immunohistochemistry, the chief cells located in the cell balls are positive for chromogranin, synaptophysin, neuron specific enolase, serotonin, neurofilament and...
Factitious disorder imposed on self, also known as Munchausen syndrome, is a factitious disorder in which those affected feign or induce disease, illness...
known as SCG3, is a protein which in humans is encoded by the SCG3 gene. The protein encoded by this gene is a member of the chromogranin/secretogranin family...
25–30. Koeslag, Johan H.; Saunders, Peter T.; Wessels, Jabus A. (1999). "The chromogranins and counter-regulatory hormones: do they make homeostatic sense...
Kendall CH, van Aswegen G, et al. (July 1989). "Developmental profile of chromogranin, hormonal peptides, and 5-hydroxytryptamine in gastrointestinal endocrine...
is immunopositivity for synaptophysin, neuron-specific enolase, and chromograninA. Elevated Ki-67 and p53 labeling index is associated with more aggressive...
varying from about 20 to 40 trillion depending on the sex, age and weight, and a roughly equal number of bacterial cells.(this have not yet been measured in...
biomarkers (including vasopressin, chromograninA, and heat shock proteins), as well as emotional stress, may play a role in the pathogenesis of atrial...
A germinoma is a type of germ-cell tumor, which is not differentiated upon examination. It may be benign or malignant. Germinomas are thought to originate...
Secretoneurin, is a 33-amino acid neuropeptide derived from secretogranin II (chromogranin C, CHGC). It is cleaved into the following 3 chains: PE-11 GAWK...
among others. Diagnostically, it is often used in combination with chromograninA. Synaptophysin has been shown to interact with AP1G1 and SIAH2. List...
prostaglandins) may contribute. Hypersecretion of glucagon, somatostatin, chromogranin, or calcitonin, ectopic secretion of ACTH resulting in Cushing's syndrome...
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