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Elevated plasma free metanephrines, plasma catecholamines, or urinary catecholamines
Treatment
Surgery, chemotherapy, radiation, and pharmacologic agents
Medication
Alpha blocker Doxazosin Prazosin Terazosin
Frequency
0.8 per 100,000 person-years [2]
Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells, also known as pheochromocytes.[3] When a tumor composed of the same cells as a pheochromocytoma develops outside the adrenal gland, it is referred to as a paraganglioma.[4] These neuroendocrine tumors typically release massive amounts of catecholamines which result in the most common symptoms, including hypertension (high blood pressure), tachycardia (fast heart rate), and sweating.[5][6] Rarely, some tumors (especially paragangliomas) may secrete little to no catecholamines, making diagnosis difficult.[6] While tumors of the head and neck are parasympathetic, their sympathetic counterparts are predominantly located in the abdomen and pelvis, particularly concentrated at the organ of Zuckerkandl.[7]
^"PHAEOCHROMOCYTOMA | Meaning & Definition for UK English". Lexico.com. Archived from the original on February 25, 2021. Retrieved 2022-08-24.
^Beard CM, Sheps SG, Kurland LT, Carney JA, Lie JT (December 1983). "Occurrence of pheochromocytoma in Rochester, Minnesota, 1950 through 1979". Mayo Clinic Proceedings. 58 (12): 802–4. PMID 6645626.
^Lenders JW, Eisenhofer G, Mannelli M, Pacak K (20–26 August 2005). "Phaeochromocytoma". Lancet. 366 (9486): 665–75. doi:10.1016/S0140-6736(05)67139-5. PMID 16112304. S2CID 208788653.
^Oyasu R, Yang XJ, Yoshida O, eds. (2008). "What is the difference between pheochromocytoma and paraganglioma? What are the familial syndromes that have pheochromocytoma as a component? What are the pathologic features of pheochromocytoma indicating malignancy?". Questions in Daily Urologic Practice. Tokyo: Springer Japan. pp. 280–284. doi:10.1007/978-4-431-72819-1_49. ISBN 978-4-431-72819-1. {{cite book}}: |work= ignored (help)
^Lenders JW, Pacak K, Walther MM, Linehan WM, Mannelli M, Friberg P, et al. (March 2002). "Biochemical diagnosis of pheochromocytoma: which test is best?". JAMA. 287 (11): 1427–34. doi:10.1001/jama.287.11.1427. PMID 11903030.
Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells, also known as pheochromocytes. When a tumor composed of the same...
Multiple endocrine neoplasia type 2 (also known as "Pheochromocytoma (codons 630 and 634) and amyloid producing medullary thyroid carcinoma", "PTC syndrome...
However, more severe disorders of the sympathoadrenal system such as pheochromocytoma (a tumor on the adrenal medulla) can affect the body's ability to maintain...
neuroendocrine tumors in the adrenal medulla, a treatable condition known as pheochromocytoma. High levels of catecholamines can also be caused by monoamine oxidase...
or accompanies a panic attack. Physiological cause could include a pheochromocytoma, heart attack, blood transfusion, or anaphylaxis. A sense of impending...
is, however, occasionally found in patients with other conditions. Pheochromocytoma also can present with angor animi, accompanied by other symptoms that...
diseases, such as Raynaud's disease, congestive heart failure (CHF), pheochromocytoma, and erectile dysfunction. Furthermore, α-blockers can occasionally...
emergency surgery at the ICU to remove a rare cancerous tumor called a pheochromocytoma after he was found unresponsive in his bed at home. On August 15, 2022...
neuroblastoma, adrenocortical carcinoma and some adrenal pheochromocytomas. Most adrenal pheochromocytomas and all adrenocortical adenomas are benign tumors...
free levels of metanephrines is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm. Lenders J, Pacak K, Walther M, Linehan...
metanephrine and normetanephrine) is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm. epinephrine Lenders J, Pacak K, Walther...
high blood pressure, kidney disease, and various types of stress. A pheochromocytoma is a rarely occurring tumor of the adrenal medulla, caused either by...
coma and pituitary apoplexy. Emergencies arising from decompensated pheochromocytomas or parathyroid adenomas are sometimes referred for emergency resection...
of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma. They are rare tumors, with an overall estimated incidence of 1 in...
can be associated with a very rare tumour known as a paraprostatic pheochromocytoma within the urinary bladder. There is no specific treatment for micturition...
body. Neoplasms include: Pheochromocytoma (most common), a catecholamine-secreting tumor of the adrenal medulla. Pheochromocytomas may generate sudden bursts...
kidney failure, those who rapidly stop blood pressure medication, pheochromocytoma, and people on a monoamine oxidase inhibitor (MAOI) who eat foods with...
the RET gene. This variant can cause medullary thyroid cancer and Pheochromocytoma. Presentation can include a Marfanoid body, enlarged lips, and ganglionueuromas...
hypertensive crisis, including a tumor. A rare, neuroendocrine tumor called a pheochromocytoma can cause a hypertensive crisis due to elevated levels of catecholamines...
receptor antagonists, it has a role in the peri-operative management of pheochromocytoma. Doxazosin is considered to be effective in reducing urinary symptom...
exocrine; endocrine gland tumors, such as a VIPoma, an insulinoma, or a pheochromocytoma, are typically not referred to as adenocarcinomas but rather are often...
blood pressure, which may be due to stress of any sort, or from a pheochromocytoma, a type of tumor involving the adrenal medulla. [citation needed] Patients...
pathological significance in the adult as a common extra-adrenal site of pheochromocytoma though the most common extra-adrenal site is in the superior para-aortic...
caused by malignancy. Pheochromocytoma originates from chromaffin cells and is a kind of neuroendocrine tumor. Pheochromocytomas are generally benign....
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