Thus, the two substrates of this enzyme are choline and acceptor, whereas its two products are betaine aldehyde and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is choline:acceptor 1-oxidoreductase. Other names in common use include choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, and choline:(acceptor) 1-oxidoreductase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, PQQ.
and 24 Related for: Choline dehydrogenase information
In enzymology, a cholinedehydrogenase (EC 1.1.99.1) is an enzyme that catalyzes the chemical reaction choline + acceptor ⇌ {\displaystyle \rightleftharpoons...
[(CH3)3NCH2CH2OH]+. Choline forms various salts, for example choline chloride and choline bitartrate. Choline is a quaternary ammonium cation. The cholines are a family...
oxidation of choline in two steps. The intermediate, betaine aldehyde, is generated by the action of the enzyme mitochondrial choline oxidase (choline dehydrogenase...
aldehyde dehydrogenase (EC 1.2.1.3) stimulates the transformation of betaine aldehyde to glycine betaine. Betaine aldehyde is a substrate for choline dehydrogenase...
PMID 18768752. Park S, Choi SG, Yoo SM, Son JH, Jung YK (2014). "Cholinedehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy"...
Feng Y, Xiong Y, Qiao T, Li X, Jia L, Han Y (December 2018). "Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy"...
post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain and support the partition of pyruvate synthesis...
that is the bioenergetic system that it affects the most. It also affects choline metabolism. The phenotypic presentation has 3 forms: a neonatal-onset form...
foods with liberalization of protein intake." Choline increases carnitine uptake and retention. Choline supplements are inexpensive, are safe (probably...
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 (MTHFD1) is a gene located in humans on chromosome 14...
source in living systems. It is formed from many precursors including choline, serine, and sarcosine. It provides a C-1 source in the biosynthesis of...
catabolism, choline metabolism, and special metabolic pathways. Defects in either of the ETF subunits or ETFDH cause multiple acyl CoA dehydrogenase deficiency...
enzyme that transforms sinapoylcholine into sinapate (sinapic acid) and choline Trans-cinnamate 2-monooxygenase, an enzyme that transforms trans-cinnamate...
acids and catabolism of amino acids and choline, as it accepts electrons from multiple acetyl-CoA dehydrogenases. In plants, ETF-Q oxidoreductase is also...
pathway that metabolizes tryptophan, and the regulation of pyruvate dehydrogenase (PDH), which converts pyruvate to acetyl CoA. Transferases are also...
disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion...
acid and methylamine. Sarcosine is an intermediate in the metabolism of choline to glycine. Sarcosine, like the related compounds dimethylglycine (DMG)...
then further metabolized into ionic acetate by the enzyme aldehyde dehydrogenase (ALDH). Acetate is not carcinogenic and has low toxicity, but has been...
cases by showing increased relative cerebral blood volume and increased choline peak, respectively, but pathology remains the gold standard for diagnosis...
problems.[citation needed] Elevated ALT may also be caused by dietary choline deficiency.[citation needed] However, elevated levels of ALT do not automatically...
Aldehyde dehydrogenase 7 family, member A1, also known as ALDH7A1 or antiquitin, is an enzyme that in humans is encoded by the ALDH7A1 gene. The protein...
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