Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Nverify (what is YN ?)
Infobox references
Chemical compound
Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. All genomes sequenced to date encode enzymes that use coenzyme A as a substrate, and around 4% of cellular enzymes use it (or a thioester) as a substrate. In humans, CoA biosynthesis requires cysteine, pantothenate (vitamin B5), and adenosine triphosphate (ATP).[2]
In its acetyl form, coenzyme A is a highly versatile molecule, serving metabolic functions in both the anabolic and catabolic pathways. Acetyl-CoA is utilised in the post-translational regulation and allosteric regulation of pyruvate dehydrogenase and carboxylase to maintain and support the partition of pyruvate synthesis and degradation.[3]
^ abDawson RM, Elliott DC, Elliott WH, Jones KM (2002). Data for Biochemical Research (3rd ed.). Clarendon Press. pp. 118–119. ISBN 978-0-19-855299-4.
^Daugherty M, Polanuyer B, Farrell M, Scholle M, Lykidis A, de Crécy-Lagard V, Osterman A (June 2002). "Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics". The Journal of Biological Chemistry. 277 (24): 21431–21439. doi:10.1074/jbc.M201708200. PMID 11923312.
^"Coenzyme A: when small is mighty". www.asbmb.org. Archived from the original on 2018-12-20. Retrieved 2018-12-19.
CoenzymeA (CoA, SHCoA, CoASH) is acoenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the...
Coenzyme Q10 (CoQ10 /ˌkoʊkjuːˈtɛn/) also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by...
Nicotinamide adenine dinucleotide (NAD) is acoenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two...
The International Coenzyme Q10 Association is a nonprofit association originally based in Ancona, Italy and currently in Seville, Spain. Since its establishment...
serves as the carbon dioxide carrier in carboxylation reactions. Biotin is acoenzyme for five carboxylase enzymes, which are involved in the catabolism of...
carried by coenzymeA formyl, methenyl or methyl groups, carried by folic acid and the methyl group, carried by S-adenosylmethionine Since coenzymes are chemically...
Coenzyme B is acoenzyme required for redox reactions in methanogens. The full chemical name of coenzyme B is 7-mercaptoheptanoylthreoninephosphate. The...
Coenzyme Q5, more commonly known as COQ5, is acoenzyme involved in the electron transport chain. It is a shorter-chain homolog of coenzyme Q10 (ubiquinone)...
Thiolases, also known as acetyl-coenzymeA acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate...
acid (vitamin B5) is a B vitamin and an essential nutrient. All animals need pantothenic acid in order to synthesize coenzymeA (CoA), which is essential...
with 30 steps in the synthesis of cholesterol from acetyl-coenzymeA. In 1971, Akira Endo, a Japanese biochemist working for the pharmaceutical company...
(PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is acoenzyme in a variety of enzymatic reactions. The International Union of Biochemistry...
Coenzyme M is acoenzyme required for methyl-transfer reactions in the metabolism of archaeal methanogens, and in the metabolism of other substrates in...
Global Information
verify (what is 
?)
