Effort to determine the DNA sequence of the chimpanzee genome
The Chimpanzee Genome Project was an effort to determine the DNA sequence of the chimpanzee genome. Sequencing began in 2005 and by 2013 twenty-four individual chimpanzees had been sequenced. This project was folded into the Great Ape Genome Project.[1]
In 2013 high resolution sequences were published from each of the four recognized[2][3] chimpanzee subspecies: Central chimpanzee, Pan troglodytes troglodytes, 10 sequences; Western chimpanzee, Pan troglodytes verus, 6 sequences; Nigeria-Cameroon chimpanzee, Pan troglodytes ellioti, 4 sequences; and Eastern chimpanzee, Pan troglodytes schweinfurthii, 4 sequences. They were all sequenced to a mean of 25-fold coverage per individual.[1]
The research showed considerable genome diversity in chimpanzees with many population-specific traits. The central chimpanzees retain the highest diversity in the chimpanzee lineage, whereas the other subspecies demonstrate signs of population bottlenecks.[4]
^ abPrado-Martinez, J.; et al. (2013). "Great ape genetic diversity and population history". Nature. 499 (7459): 471–475. Bibcode:2013Natur.499..471P. doi:10.1038/nature12228. PMC 3822165. PMID 23823723.
^Groves, Colin P. (2001). Primate Taxonomy. Washington, DC: Smithsonian Institution Press. pp. 303–307. ISBN 978-1-56098-872-4.
^Hof, J.; Sommer, V. (2010). Apes Like Us: Portraits of a Kinship. Mannheim: Panorama. p. 114. ISBN 978-3-89823-435-1.
^de Manuel, M.; et al. (2016). "Chimpanzee genomic diversity reveals ancient admixture with bonobos". Science. 354 (6311): 477–48. Bibcode:2016Sci...354..477D. doi:10.1126/science.aag2602. PMC 5546212. PMID 27789843.
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