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Childhood absence epilepsy information


Childhood absence epilepsy (CAE), formerly known as pyknolepsy, is an idiopathic generalized epilepsy which occurs in otherwise normal children. The age of onset is between 4–10 years with peak age between 5–7 years. Children have absence seizures which although brief (~4–20 seconds), they occur frequently, sometimes in the hundreds per day. The absence seizures of CAE involve abrupt and severe impairment of consciousness. Mild automatisms are frequent, but major motor involvement early in the course excludes this diagnosis. The EEG demonstrates characteristic "typical 3Hz spike-wave" discharges. The presence of any other seizure type at time of diagnosis rules out the diagnose of CAE.[1] Prognosis is usually good in well-defined cases of CAE with most patients "growing out" of their epilepsy.[2]

  1. ^ Hirsch, Edouard; French, Jacqueline; Scheffer, Ingrid E.; Bogacz, Alicia; Alsaadi, Taoufik; Sperling, Michael R.; Abdulla, Fatema; Zuberi, Sameer M.; Trinka, Eugen; Specchio, Nicola; Somerville, Ernest (June 2022). "ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions". Epilepsia. 63 (6): 1475–1499. doi:10.1111/epi.17236. ISSN 1528-1167. PMID 35503716. S2CID 248504453.
  2. ^ Hirsch E, Thomas P, Panayiotopoulos C (2007). "Childhood and absence epilepsies". Epilepsy: A Comprehensive Textbook: 2397–2411.

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notable postictal state). Absence seizures are most common in children. They affect both sides of the brain. Childhood absence epilepsy represents a significant...

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Childhood absence epilepsy

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Childhood absence epilepsy (CAE), formerly known as pyknolepsy, is an idiopathic generalized epilepsy which occurs in otherwise normal children. The age...

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Epilepsy syndromes

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idiopathic generalized epilepsies (specifically childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized...

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examples are benign rolandic epilepsy (2.8 per 100,000), childhood absence epilepsy (0.8 per 100,000) and juvenile myoclonic epilepsy (0.7 per 100,000). Severe...

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Benign Rolandic epilepsy or self-limited epilepsy with centrotemporal spikes (formerly benign childhood epilepsy with centrotemporal spikes (BECTS)) is...

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Generalized epilepsy

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syndromes, including myoclonic epilepsy, familial neonatal convulsions, childhood absence epilepsy, absence epilepsy, infantile spasms (West's syndrome)...

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Idiopathic generalized epilepsy

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disorder also have absence seizures. This is believed to be a polygenic disorder. Also known as pyknolepsy, childhood absence epilepsy (CAE) represents...

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of 15 years. Approximately 15% of children with childhood absence epilepsy and juvenile absence epilepsy subsequently develop JME. In most cases, myoclonic...

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Splice site mutation

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in protein expression. A study has also shown that a type of Childhood Absence Epilepsy (CAE) causing febrile seizures may be linked to a splice site...

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GABRB3

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GABRB3 gene exhibit absence seizures. Reduced expression of the beta-3 subunit is a potential contributor to childhood absence epilepsy. GABAA receptor Heritability...

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Generalized epilepsy with febrile seizures plus

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are found in several epilepsies, including Childhood Absence Epilepsy, Juvenile Myoclonic Epilepsy, and Genetic Generalized Epilepsy. Some cases of Dravet...

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condition epilepsy. Following from that, there is a short list of people who have received a speculative, retrospective diagnosis of epilepsy. Finally...

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to treat epilepsy and bipolar disorder and prevent migraine headaches. They are useful for the prevention of seizures in those with absence seizures,...

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tasks Caprine arthritis encephalitis, a disease in goats Childhood absence epilepsy, a childhood seizure disorder Carbonic anhydrase enzyme, that catalyzes...

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Epilepsy is a neurological condition of recurrent episodes of unprovoked epileptic seizures. A seizure is an abnormal neuronal brain activity that can...

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GAERS or Genetic Absence Epilepsy Rat from Strasbourg is a recognized animal model of absence epilepsy, a typical childhood form of epilepsy characterized...

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GLUT1

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the exercised limbs. Some patients may also have epilepsy, most commonly childhood absence epilepsy. Mild mental retardation may also occur. In some patients...

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symptoms and EEG may appear like Generalized epilepsy, Juvenile myoclonic epilepsy, benign childhood myoclonic epilepsy, and Huntington's disease. It is crucial...

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Myoclonus

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