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Chemotactic selection information


Chemotaxis receptors are expressed in the surface membrane with diverse dynamics, some of them have long-term characteristics as they are determined genetically, others have short-term moiety as their assembly is induced ad hoc in the presence of the ligand. The diverse feature of the chemotaxis receptors and ligands provides the possibility to select chemotactic responder cells with a simple chemotaxis assay. By chemotactic selection we can determine whether a still not characterized molecule acts via the long- or the short-term receptor pathway. Recent results proved that chemokines (e.g. IL-8, RANTES) are working on long-term chemotaxis receptors, while vasoactive peptides (e.g. endothelin) act more on the short-term ones. Term chemotactic selection is also used to design a technique which separates eukaryotic or prokaryotic cells upon their chemotactic responsiveness to selector ligands.

Chemotactic selection
Chemotactic selection

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Chemotactic selection

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provides the possibility to select chemotactic responder cells with a simple chemotaxis assay. By chemotactic selection we can determine whether a still...

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Chemotaxis

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for the possibility of selecting chemotactic responder cells with a simple chemotaxis assay By chemotactic selection, we can determine whether a still-uncharacterized...

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Interleukin 8

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in the innate immune system response. IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells...

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Macrophage

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Eichenfield DZ, Spann NJ, et al. (December 2014). "Environment drives selection and function of enhancers controlling tissue-specific macrophage identities"...

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CCR5

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respectively), and CCL3L1. CCR5 furthermore interacts with CCL5 (a chemotactic cytokine protein also known as RANTES). CCR5 is predominantly expressed...

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List of portmanteaus

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from carbon and corundum cermet, from ceramic and metal chemokine, from chemotactic and cytokine clopen set, from closed-open set contrail, from condensation...

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Sperm chemotaxis

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but it is also a mechanism of sperm selection. Importantly, the fraction of capacitated (and, hence, chemotactically responsive) spermatozoa is low (~10%...

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Antibody

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following: Lysis of the foreign cell Encouragement of inflammation by chemotactically attracting inflammatory cells More indirectly, an antibody can signal...

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Adaptive immune system

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as bacteria, parasites or toxins in the tissues and then migrate, via chemotactic signals, to the T cell-enriched lymph nodes. During migration, dendritic...

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Duffy antigen system

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for chemokines of both the C-C and C-X-C families, including: monocyte chemotactic protein-1 (MCP-1) - CCL2 regulated upon activation normal T expressed...

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Channel catfish

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depend solely on visual cues. Instead, they are known to rely heavily on chemotactic cues. Sound production may be another important means of communication...

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Eicosanoid

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pathogens, or stimuli made by nearby cells, tissues, or pathogens such as chemotactic factors, cytokines, growth factors, and even certain eicosanoids. The...

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Egg jelly

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example, sperm in Lytechinus variegatus, the green sea urchin, are not chemotactically attracted to the jelly or the egg. The egg jelly is located immediately...

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Innate immune system

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and heparin, along with various hormonal mediators and chemokines, or chemotactic cytokines into the environment. Histamine dilates blood vessels, causing...

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Antigen presentation

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lymph nodes. APCs undergo a process of maturation while migrating, via chemotactic signals, to lymphoid tissues, in which they lose the phagocytic capacity...

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Drug delivery

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membrane capsule Bioavailability Bovine submaxillary mucin coatings Chemotactic drug-targeting Drug delivery to the brain Drug carrier Gated drug delivery...

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CCL22

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functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes"....

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CXCL11

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do the other ligands for this receptor, CXCL9 and CXCL10. CXCL11 is chemotactic for activated T cells. Its gene is located on human chromosome 4 along...

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Mating in fungi

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mating type, it approaches the source through chemotropic growth or chemotactic movement if it is a gamete. Some of the species within Basidiomycota...

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Copiotroph

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out of a microbe’s cell to facilitate movement. Copiotrophs are also chemotactic, meaning they can detect nutrients in the environment. These help the...

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Sperm guidance

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but it is also a mechanism of sperm selection. Importantly, the fraction of capacitated (and, hence, chemotactically responsive) spermatozoa is low (~10%...

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C1QTNF3

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Sugano S, Isogai T (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from...

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CCL21

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bound to glycosaminoglycans, and endothelial cells and it induces the chemotactic migration of T cells and the cell adhesion caused by integrin activation...

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Microswimmer

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PMID 30236447. S2CID 52310451. Plutnar, Jan; Pumera, Martin (2019). "Chemotactic Micro- and Nanodevices". Angewandte Chemie International Edition. 58...

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Benoxaprofen

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benoxaprofen acts directly on mononuclear cells. It inhibits their chemotactic response by inhibiting the lipoxygenase enzyme. Benoxaprofen is an analgesic...

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Michael Eisenbach

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that only a small fraction of the spermatozoa (~10% in humans) are chemotactically responsive and that the responsive spermatozoa are the capacitated...

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