In molecular biology, chaperone DnaJ, also known as Hsp40 (heat shock protein 40 kDa), is a molecular chaperone protein. It is expressed in a wide variety of organisms from bacteria to humans.[1][2]
^Qiu XB, Shao YM, Miao S, Wang L (November 2006). "The diversity of the DnaJ/Hsp40 family, the crucial partners for Hsp70 chaperones". Cellular and Molecular Life Sciences. 63 (22): 2560–70. doi:10.1007/s00018-006-6192-6. PMC 11136209. PMID 16952052. S2CID 21325339.
^Caplan AJ, Cyr DM, Douglas MG (June 1993). "Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins". Molecular Biology of the Cell. 4 (6): 555–63. doi:10.1091/mbc.4.6.555. PMC 300962. PMID 8374166.
In molecular biology, chaperoneDnaJ, also known as Hsp40 (heat shock protein 40 kDa), is a molecular chaperone protein. It is expressed in a wide variety...
DnaJ homolog subfamily C member 28 is a protein that in humans is encoded by the DNAJC28 gene. It's a member of chaperoneDnaJ family. The family is also...
Young R (June 2017). "MS2 Lysis of Escherichia coli Depends on Host ChaperoneDnaJ". Journal of Bacteriology. 199 (12). doi:10.1128/JB.00058-17. PMC 5446614...
foldase systems are the GroEL/GroES and the DnaK/DnaJ/GrpE system. Holdase Chaperonin Co-chaperone Hoffmann, J. R. H.; Linke, K.; Graf, P. C.; Lilie, H.; Jakob...
important part of the cell's machinery for protein folding, performing chaperoning functions, and helping to protect cells from the adverse effects of physiological...
kind of molecular chaperones that assist the non-covalent folding of proteins in an ATP-independent manner. Examples of holdases are DnaJ and Hsp33. Holdases...
Once DnaJ, a co-chaperone, brings an unfolded protein to DnaK ATP is hydrolyzed to ADP to facilitate folding of the protein. At this point, the DnaK•ADP...
16. This protein belongs to the DNAJ/Hsp40 protein family, which is known for binding and activating Hsp70 chaperone proteins to perform protein folding...
DnaJ homolog subfamily B member 6 is a protein that in humans is encoded by the DNAJB6 gene. This gene encodes a member of the DNAJ protein family. DNAJ...
Tyler JK (January 2010). "Chaperoning histones during DNA replication and repair". Cell. 140 (2): 183–195. doi:10.1016/j.cell.2010.01.004. PMC 3433953...
the DNAJC30 gene. This intronless gene encodes a member of the DNAJ molecular chaperone homology domain-containing protein family. This gene is deleted...
the genetic code specifies how DNA makes proteins, and the histone code regulates histone-DNA interactions, the chaperone code controls how proteins are...
wound healing or tissue remodeling. Many members of this group perform chaperone functions by stabilizing new proteins to ensure correct folding or by...
that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly...
Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in...
chemically extracted from host chaperone proteins then heated, causing thermal dissociation of the DNA strands. Two new cDNA strands are built from the original...
known as DnaJ homolog subfamily C member 29 (DNAJC29) is a protein that in humans is encoded by the SACS gene. Sacsin is a Hsp70 co-chaperone. This gene...
proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA molecule to maintain its integrity. These chromosomes...
relieve the tight association of histones for DNA removal remains unanswered. Another histone chaperone that associates with the replisome is Asf1, which...
"Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress & Chaperones. 5 (2): 98–112...
enter the host. The cDNA copy is then made through reverse transcription of the viral RNA, a process facilitated by the chaperone CypA and a viral capsid...
DnaJ homolog subfamily C member 2 is a protein that in humans is encoded by the DNAJC2 gene. This gene is a member of the M-phase phosphoprotein (MPP)...
"Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress & Chaperones. 5 (2): 98–112...
Mesoderm development LRP chaperone, or MESD, is a protein that in humans is encoded by the MESD gene. GRCh38: Ensembl release 89: ENSG00000117899 – Ensembl...
DnaJ homolog subfamily C member 1 is a protein that in humans is encoded by the DNAJC1 gene. DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin...