Cefoxitin is a second-generation cephamycin antibiotic developed by Merck & Co., Inc. from Cephamycin C in the year following its discovery, 1972. It was synthesized in order to create an antibiotic with a broader spectrum.[4] It is often grouped with the second-generation cephalosporins.[5] Cefoxitin requires a prescription and as of 2010 is sold under the brand name Mefoxin by Bioniche Pharma, LLC. The generic version of cefoxitin is known as cefoxitin sodium.[6][7]
^"Cefoxitin International". Drugs.com. 2 November 2020. Retrieved 8 November 2020.
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
^Cite error: The named reference Cefoxitin FDA label was invoked but never defined (see the help page).
^Gootz TD (January 1990). "Discovery and development of new antimicrobial agents". Clinical Microbiology Reviews. 3 (1): 13–31. doi:10.1128/cmr.3.1.13. PMC 358138. PMID 2404566.
^Levy SB (2013-11-11). The Antibiotic Paradox: How Miracle Drugs Are Destroying the Miracle. Springer. ISBN 978-1-4899-6042-9.
^"Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations". www.accessdata.fda.gov. Retrieved 2017-05-04.
^"Supplement Approval" (PDF). Food and Drug Administration. Department of Health and Human Services.
Cefoxitin is a second-generation cephamycin antibiotic developed by Merck & Co., Inc. from Cephamycin C in the year following its discovery, 1972. It...
and Gram-negative organisms must be covered. Out of the cephalosporins, cefoxitin and cefotetan can be used to cover Gram-positive bacteria, Gram-negative...
is lacking for this indication.[citation needed] Cephamycins include: Cefoxitin Cefotetan Cefmetazole Oreste A. Mascaretti (2003). Bacteria Versus Antibacterial...
cefapirin, cefradine, and cefadroxil are drugs belonging to this group. Cefoxitin, cefuroxime, cefaclor, cefprozil, and cefmetazole are classed as second-generation...
administered to them as inpatients or outpatients. Typical regimens include cefoxitin or cefotetan plus doxycycline, and clindamycin plus gentamicin. An alternative...
third-generation cephalosporins, but remain susceptible to imipenem, cefoxitin, and amoxicillin combined with clavulanic acid. Although resistant strains...
have displayed increasing resistance to antimicrobial agents such as cefoxitin, clindamycin, metronidazole, carbapenems, & fluoroquinolones. Resistance...
disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Cefoxitin Cefotetan Cefotan Cefamandole Cefmetazole Cefonicid Loracarbef Cefprozil...
pelvic inflammatory disease: comparison of cefotetan plus doxycycline and cefoxitin plus doxycycline". American Journal of Obstetrics and Gynecology. 158...
This bacterium is susceptible to the β-lactam antibiotics imipenem, cefoxitin, and ticarcillin. B. wadsworthia is a Gram-negative, catalase-positive...
resistance of P. penneri to cefuroxime and the marked inhibitory activity of cefoxitin against this species also distinguishes P. penneri from the other Proteus...
on symptoms, ultrasound, laparoscopic surgery Typical regimens include cefoxitin or cefotetan plus doxycycline, and clindamycin plus gentamicin. No Bordetella...
Tsai JC, Liaw SJ, Ho SW, Luh KT (September 2002). "High incidence of cefoxitin and clindamycin resistance among anaerobes in Taiwan". Antimicrobial Agents...
gel electrophoresis, which can be costly, tedious, and unpredictable. cefoxitin disc diffusion uses phenotypic resistance to test not only for methicillin...
using biochemical or phenotypic methods, such as disc diffusion. Although cefoxitin disks have been used, oxacillin disks are considered to be much more sensitive...
rifampicin, fusidic acid, and fosfomycin. P. gergoviae is also resistant to cefoxitin, likely due to β-lactamase production. Brenner, D. J.; Richard, C.; Steigerwalt...
for most infections are metronidazole, clindamycin, chloramphenicol, cefoxitin, a penicillin (i.e. ticarcillin, ampicillin, piperacillin) and a beta-lactamase...
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