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Chemical compound
Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.[citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich.[1]
Carnosine is naturally produced by the body in the liver[2] from beta-alanine and histidine. Like carnitine, carnosine is composed of the root word carn, meaning "flesh", alluding to its prevalence in meat.[3] There are no plant-based sources of carnosine.[4] Carnosine is readily available as a synthetic nutritional supplement.
^Gulewitsch, Wl.; Amiradžibi, S. (1900). "Ueber das Carnosin, eine neue organische Base des Fleischextractes". Berichte der Deutschen Chemischen Gesellschaft. 33 (2): 1902–1903. doi:10.1002/cber.19000330275.
^Trexler, Eric T.; Smith-Ryan, Abbie E.; Stout, Jeffrey R.; Hoffman, Jay R.; Wilborn, Colin D.; Sale, Craig; Kreider, Richard B.; Jäger, Ralf; Earnest, Conrad P.; Bannock, Laurent; Campbell, Bill (2015-07-15). "International society of sports nutrition position stand: Beta-Alanine". Journal of the International Society of Sports Nutrition. 12: 30. doi:10.1186/s12970-015-0090-y. ISSN 1550-2783. PMC 4501114. PMID 26175657.
^Hipkiss, A. R. (2006). "Does chronic glycolysis accelerate aging? Could this explain how dietary restriction works?". Annals of the New York Academy of Sciences. 1067 (1): 361–8. Bibcode:2006NYASA1067..361H. doi:10.1196/annals.1354.051. PMID 16804012. S2CID 41175541.
^Alan R. Hipkiss (2009). "Chapter 3: Carnosine and Its Possible Roles in Nutrition and Health". Advances in Food and Nutrition Research.
Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle...
compound chemically related to the dipeptide carnosine. The NAC molecular structure is identical to carnosine with the exception that it carries an additional...
Carnosine synthase (EC 6.3.2.11) is an enzyme that catalyzes the chemical reaction ATP + L-histidine + beta-alanine ⇌ {\displaystyle \rightleftharpoons...
3-methylhistidine. Anserine is a derivative of carnosine, which has been methylated. Both anserine and carnosine chelate copper. Due to its methylation, anserine...
certain methyltransferase enzymes. Histidine is also a precursor for carnosine biosynthesis, which is a dipeptide found in skeletal muscle. In Actinomycetota...
enzyme that splits dipeptides into their two amino acid constituents). Carnosine is a dipeptide composed of beta-alanine and histidine, and is found in...
life span of animals. Some possible geroprotectors include melatonin, carnosine, metformin, rapamycin, nicotinamide mononucleotide (NMN) and delta sleep-inducing...
September 1933) was a Russian Empire and Soviet biochemist who first isolated carnosine from mammalian muscle. Gulevich graduated in 1890 and received the degree...
β-alanine, GADL1 consequently plays a role in the production of carnosine. Carnosine and taurine have multiple biological functions such as calcium regulation...
investigating yoga as a treatment for GWI. An amino acid supplement containing L-carnosine was found to reduce irritable bowel syndrome-associated diarrhea in a...
the effects of a nutraceutical composed of MSM, hyaluronic acid, and L-carnosine. The results from RCT showed broad improvements in facial skin hydration...
with the structure NH+3−CXY−CXY−CO−2, such as β-alanine, a component of carnosine and a few other peptides, are β-amino acids. Ones with the structure...
(N-L-α-aspartyl-L-phenylalanine 1-methyl ester) is an artificial sweetener. Carnosine (beta-alanyl-L-histidine) and Anserine (beta-alanyl-N-methyl histidine)...
Corporation, Salt Lake City, Utah, U.S N-Acetylcarnosine, a compound related to carnosine N-Acetylcysteine, a medication Nucleus accumbens, a region in the brain...
Cytosolic non-specific dipeptidase (EC 3.4.13.18) also known as carnosine dipeptidase 2 is an enzyme that in humans is encoded by the CNDP2 gene. This...
Several other treatments that have antioxidant properties, including carnosine, have also been reported to significantly improve ASD behaviors, suggesting...
C9H14N4O3 (molar mass: 226.24 g/mol, exact mass: 226.1066 u) may refer to: Carnosine Nimorazole This set index page lists chemical structure articles associated...
Daniel S.; Thatcher, Rhys; Playford, Raymond J. (August 2016). "Zinc carnosine works with bovine colostrum in truncating heavy exercise–induced increase...
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