CITED2 information

CITED2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P4Q, 1R8U
Identifiers
Aliases	CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
External IDs	OMIM: 602937; MGI: 1306784; HomoloGene: 4433; GeneCards: CITED2; OMA:CITED2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	139,374,648 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	17,601,422 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; beta cell; ; gastric mucosa; ; left ovary; ; right ovary; ; nipple; ; decidua; ; left uterine tube; ; right lung; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	medullary collecting duct; ; renal corpuscle; ; left lung lobe; ; primitive streak; ; lobe of cerebellum; ; habenula; ; decidua; ; cerebellar vermis; ; vestibular membrane of cochlear duct; ; retina;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; transcription corepressor activity; DNA-binding transcription factor activity; chromatin binding; LBD domain binding; protein binding; histone acetyltransferase binding; protein domain specific binding;
Cellular component	cytoplasm; nucleus; nucleoplasm; protein-containing complex;
Biological process	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry; adrenal cortex formation; positive regulation of transforming growth factor beta receptor signaling pathway; cell differentiation; response to hypoxia; regulation of transcription, DNA-templated; positive regulation of cell-cell adhesion; embryonic heart tube left/right pattern formation; ventricular septum morphogenesis; outflow tract morphogenesis; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; spleen development; negative regulation of gene expression; transcription, DNA-templated; response to fluid shear stress; response to estrogen; positive regulation of transcription, DNA-templated; multicellular organism development; heart development; determination of left/right symmetry; positive regulation of gene expression; negative regulation of cell migration; positive regulation of cell cycle; regulation of animal organ formation; sex-determination system; positive regulation of peroxisome proliferator activated receptor signaling pathway; liver development; left/right pattern formation; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; cell population proliferation; negative regulation of transcription, DNA-templated; left/right axis specification; positive regulation of male gonad development; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; positive regulation of nucleic acid-templated transcription; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	10370
	17684
	ENSG00000164442
	ENSMUSG00000039910
	Q99967
	O35740
	NM_006079; NM_001168388; NM_001168389
	NM_010828
	NP_001161860; NP_001161861; NP_006070
	NP_034958
	Wikidata
View/Edit Human	View/Edit Mouse

Cbp/p300-interacting transactivator 2 is a protein that in humans is encoded by the CITED2 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164442 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039910 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shioda T, Fenner MH, Isselbacher KJ (Oct 1996). "msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12298–303. Bibcode:1996PNAS...9312298S. doi:10.1073/pnas.93.22.12298. PMC 37985. PMID 8901575.
^ Leung MK, Jones T, Michels CL, Livingston DM, Bhattacharya S (Nov 1999). "Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1". Genomics. 61 (3): 307–13. doi:10.1006/geno.1999.5970. PMID 10552932.
^ "Entrez Gene: CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164442 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000039910 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8901575-5] Shioda T, Fenner MH, Isselbacher KJ (Oct 1996). "msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12298–303. Bibcode:1996PNAS...9312298S. doi:10.1073/pnas.93.22.12298. PMC 37985. PMID 8901575.

[pmid10552932-6] Leung MK, Jones T, Michels CL, Livingston DM, Bhattacharya S (Nov 1999). "Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1". Genomics. 61 (3): 307–13. doi:10.1006/geno.1999.5970. PMID 10552932.

[entrez-7] "Entrez Gene: CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2".

CITED2 information

and 9 Related for: CITED2 information

CITED2

EP300

TAZ zinc finger

Wilms tumor protein

Metabolic regulation of hematopoiesis

LHX2

Nodal homolog

TFAP2A

TFAP2C