Skin condition characterized by small bumps caused by overproduction of keratin
Medical condition
Keratosis pilaris
Other names
Follicular keratosis, lichen pilaris
Condition on a calf
Specialty
Dermatology
Keratosis pilaris (KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin[1]) is a common, autosomal-dominant, genetic condition of the skin's hair follicles characterized by the appearance of possibly itchy, small, gooseflesh-like bumps, with varying degrees of reddening or inflammation.[2] It most often appears on the outer sides of the upper arms (the forearms can also be affected), thighs, face, back, and buttocks;[2] KP can also occur on the hands, and tops of legs, sides, or any body part except glabrous (hairless) skin (like the palms or soles of feet).[3] Often the lesions can appear on the face, which may be mistaken for acne[4] or folliculitis.
The several types of KP have been associated with pregnancy, type 1 diabetes mellitus, obesity, dry skin, allergic diseases (e.g., atopic dermatitis), and rarely cancer.[1] Many rarer types of the disorder are part of inherited genetic syndromes.[1]
The cause of KP is not completely understood. As of 2018, KP is thought to be due to abnormalities in the process of depositing the protein keratin in hair follicles, abnormalities in the hair shaft, or both.[1] KP is usually diagnosed by a medical professional based on the appearance of the skin, but dermoscopy can be used, as well, if the diagnosis is unclear.[1] Variants of the ABCA12 gene have been associated with KP.[5]
KP is the most common disorder of the hair follicle in children.[1]
How common it is in adults is unclear since keratosis pilaris is an underreported condition and the actual prevalence of the condition may be higher than estimated.[6] No single approach has been found to completely cure KP, but treatments can improve the cosmetic appearance of the condition. Treatment includes the application of topical preparations of moisturizers and medications such as glycolic acid, lactic acid, salicylic acid, urea, or retinoids to the skin.[1] Fractional carbon dioxide lasers and Nd:YAG laser therapies are also effective.[1]
^ abcdefghCite error: The named reference Wang2018 was invoked but never defined (see the help page).
^ abPanchaprateep R, Tanus A, Tosti A (March 2015). "Clinical, dermoscopic, and histopathologic features of body hair disorders". Journal of the American Academy of Dermatology. 72 (5): 890–900. doi:10.1016/j.jaad.2015.01.024. PMID 25748313.
^Liu F, Yang Y, Zheng Y, Liang YH, Zeng K (September 2018). "Mutation and expression of ABCA12 in keratosis pilaris and nevus comedonicus". Molecular Medicine Reports. 18 (3): 3153–3158. doi:10.3892/mmr.2018.9342. PMC 6102636. PMID 30066947.
^Pennycook KB, McCready TA (June 27, 2022). Keratosis Pilaris in StatPearls. PMID 31536314.
Keratosispilaris (KP; also follicular keratosis, lichen pilaris, or colloquially chicken skin) is a common, autosomal-dominant, genetic condition of the...
to: actinic keratosis (also known as solar keratosis), a premalignant condition chronic scar keratosis hydrocarbon keratosiskeratosispilaris (KP, also...
"senile keratosis" a misnomer. The sign of Leser-Trélat Inverted follicular keratosis is generally thought to be a rare variant of seborrheic keratosis, but...
Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, is a pre-cancerous area of thick, scaly, or crusty skin. Actinic keratosis is...
Keratosispilaris atrophicans faciei begins in infancy as follicular papules with perifollicular erythema.: 762 Initially, the lesions are restricted...
similarly appearing white lesions that are caused by reactive keratosis (smoker's keratosis or frictional keratoses e.g. morsicatio buccarum) are not considered...
as well as pinpoint hyperkeratoses. There is a benign condition called keratosis palmaris et plantaris, which produces corns in the creases of the fingers...
keratotic papules that are grouped into large patches. It is a variant of keratosispilaris named for its resemblance to a patch of lichen. It appears as a cluster...
treatment of mild-moderate acne, and is also used off-label to treat keratosispilaris as well as other skin conditions. Studies have found adapalene is...
Devergie M. G. A. (1856). "[Pityriasis pilaris, a skin disease not described by dermatologists] (Pityriasis pilaris, maladie de la peau non décrite par les...
cohesion of cells will block or "cap" the hair follicle (leading to keratosispilaris) or clog the sebaceous/oil duct (leading to acne). Pathogens may also...
separate occasions that she experiences synesthesia, and also has keratosispilaris and alopecia areata. She has also been open about her struggles with...
called skin tags Dermatology List of cutaneous conditions Seborrheic keratosis Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology:...
endogenous phototoxicity, nevus of Ota, café au lait macules, seborrheic keratosis, Poikiloderma of Civatte, acquired bilateral nevus of ota-like macules...
recur even after symptoms have gone away.[citation needed] Ingrown hair Keratosis Winters RD, Mitchell M (18 September 2019). "Folliculitis". Folliculitis...
of hyperkeratotic areas. Follicular hyperkeratosis, also known as keratosispilaris (KP), is a skin condition characterized by excessive development of...
and face; also palmo plantar keratosis has been reported. Lichenoid keratoses (also known as "benign lichenoid keratosis", and "Solitary lichen planus")...
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