The Bioinformatics Resource Centers (BRCs) are a group of five Internet-based research centers established in 2004 and funded by NIAID (the National Institute of Allergy and Infectious Diseases.)[1] The BRCs were formed in response to the threats posed by emerging and re-emerging pathogens, particularly Centers for Disease Control and Prevention (CDC) Category A, B, and C pathogens,[2] and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them.
The main goals of the BRCs are as follows:
1) To create comprehensive databases of reliable, up-to-date bioinformatic data (genetic, proteomic, biochemical, or microbiological) related to the pathogens of interest;
2) To provide researchers with easy access to this data through Internet-based search and data retrieval user interfaces;
3) To provide researchers with relevant, state-of-the art computational tools for bioinformatic analysis of these data.
Currently there are two BRC contracts awarded, one for bacteria and viruses, and the other for vectors, Eukaryotic protozoan and fungal pathogens and host response to pathogen infections.
Bioinformatics Resource Centers
Name
Acrono name
Contributing organization(s)
Organisms covered
Example organisms (CDC Category)
Eukaryotic Pathogen, Vector and Host Informatics Resources
VEuPathDB
University of Pennsylvania
University of Notre Dame
University of Georgia
Imperial College of London
EBI-ENSEMBL
All relevant pathogenic protozoa, fungi, vectors of pathogens and selected host organisms. In addition, important non-pathogenic organisms are included for phylogenetic inferences.
^Overview, Bioinformatics Resource Centers Archived May 15, 2008, at the Wayback Machine, National Institute of Allergy and Infectious Diseases (NIAID), January 10, 2008.
^CDC Bioterrorism Agents and Diseases (By Category) Archived 2014-07-22 at the Wayback Machine, Centers for Disease Control and Prevention (Department of Health and Human Services), accessed July 8, 2008.
and 30 Related for: Bioinformatics Resource Centers information
The BioinformaticsResourceCenters (BRCs) are a group of five Internet-based research centers established in 2004 and funded by NIAID (the National Institute...
and a variety of tools for bioinformatic genome analysis. This resource was one of eight BRCs (BioinformaticsResourceCenters) funded by NIAID with the...
PATRIC (Pathosystems Resource Integration Center) was a bacterial bioinformatics website from the BioinformaticsResourceCenter, originally created in...
emerging/reemerging infectious diseases. ViPR is one of the five BioinformaticsResourceCenters (BRC) funded by NIAID, a component of the National Institutes...
VectorBase is one of the five BioinformaticsResourceCenters (BRC) funded by the National Institute of Allergy and Infectious Diseases (NIAID), a component...
Protein Information Resource (PIR), located at Georgetown University Medical Center, is an integrated public bioinformaticsresource to support genomic...
The National Microbial Pathogen Data Resource was one of the eight BioinformaticsResourceCenters funded by the National Institutes of Allergy and Infectious...
Machine learning in bioinformatics is the application of machine learning algorithms to bioinformatics, including genomics, proteomics, microarrays, systems...
an integrated resource for the study of methionine residues sulfoxidation". Bioinformatics. 35 (22): 4849–4850. doi:10.1093/bioinformatics/btz462. PMC 6853639...
Genomic Research Center for Biomolecular Science and Engineering Netherlands Bioinformatics Centre COSBI Institute of Bioinformatics (IOB) Max Planck...
2006 under a National Institutes of Health program to create BioinformaticsResourceCenters to facilitate research on pathogens that may pose biodefense...
Pork warnings over new stomach illness Yersinia genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID YersiniaBase...
analysis resource to search, analyze, visualize, save and share data for influenza virus research. IRD is one of the five BioinformaticsResourceCenters (BRC)...
PATRIC, a BioinformaticsResourceCenter funded by NIAID Vaccine Resource Library: Shigellosis and enterotoxigenic Escherichia coli (ETEC) US Centers for Disease...
The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland. The...
book}}: CS1 maint: postscript (link) Escherichia genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID Portal: Biology...
PMID 32373076. Bartonella genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID New Bartonella Species That Infects Humans Discovered...
relevant to biotechnology and biomedicine and is an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences...
Data related to Staphylococcus at Wikispecies Staphylococcus genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID...
related to Coxiella burnetii. Coxiella burnetii genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID Portal: Biology...
genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID Pathema-Burkholderia Resource Burkholderia Genome Database...
enterocolitica genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID Yersinia enterocolitica in the NCBI Taxonomy...
Streptococcus genomes and related information at PATRIC, a BioinformaticsResourceCenter funded by NIAID The Canadian Strep B Foundation Archived 2013-05-02...
about 60,000 unique visitors per month. TAIR is located at Phoenix Bioinformatics, and funded by subscriptions. From its inception in 1999 to 2013, TAIR...
Global Information