Bacteriocins are proteinaceous or peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are similar to yeast and paramecium killing factors, and are structurally, functionally, and ecologically diverse. Applications of bacteriocins are being tested to assess their application as narrow-spectrum antibiotics.[1]
Bacteriocins were first discovered by André Gratia in 1925.[2][3] He was involved in the process of searching for ways to kill bacteria, which also resulted in the development of antibiotics and the discovery of bacteriophage, all within a span of a few years. He called his first discovery a colicine because it was made by E. coli.
^Cotter PD, Ross RP, Hill C (February 2013). "Bacteriocins - a viable alternative to antibiotics?". Nature Reviews. Microbiology. 11 (2): 95–105. doi:10.1038/nrmicro2937. PMID 23268227. S2CID 37563756.
^Gratia A (1925). "Sur un remarquable exemple d'antagonisme entre deux souches de coilbacille" [On a remarkable example of antagonism between two strains of coilbacille]. Compt. Rend. Soc. Biol. (in French). 93: 1040–2. NAID 10027104803.
^Gratia JP (October 2000). "André Gratia: a forerunner in microbial and viral genetics". Genetics. 156 (2): 471–6. doi:10.1093/genetics/156.2.471. PMC 1461273. PMID 11014798.
Bacteriocins are proteinaceous or peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are...
peptides, termed bacteriocins. Bacteriocins for which disulfide bonds are the only modification to the peptide are Class II bacteriocins. One important...
the oral probiotic demonstrated no discernible benefits. Sakacins are bacteriocins of class II produced by L. sakei. In strain CCUG 42687, their production...
Bacteriocin AS-48 is a cyclic peptide antibiotic produced by the eubacteria Enterococcus faecalis (Streptococcus faecalis) that shows a broad antimicrobial...
produces Lactocillin. Lactobacillus gasseri produces gassericin A, a bacteriocin. Johnson, J. L.; Phelps, C. F.; Cummins, C. S.; London, J.; Gasser, F...
lantibiotics are a class of more extensively modified bacteriocins, also called Class I bacteriocins. (Bacteriocins for which disulfide bonds are the only modification...
A colicin is a type of bacteriocin produced by and toxic to some strains of Escherichia coli. Colicins are released into the environment to reduce competition...
acidification inhibits the growth of spoilage agents. Proteinaceous bacteriocins are produced by several LAB strains and provide an additional hurdle...
infections. Some strains of S. salivarius are found to produce BLIS (Bacteriocin-like Inhibitory Substances) which are antimicrobial peptides. These peptides...
1960s. While most bacteriocins generally inhibit only closely related species, nisin is a rare example of a "broad-spectrum" bacteriocin effective against...
II may refer to: Class II antiarrhythmic Class II appliance Class II bacteriocin Class II cabinet Class II electrical appliance Class II gaming Class...
Microcins are very small bacteriocins, composed of relatively few amino acids. For this reason, they are distinct from their larger protein cousins. The...
Biologist Benjamin C. Kirkup Jr. demonstrated that these antibiotics, bacteriocins, were active as Escherichia coli compete with each other in the intestines...
interacts with many pathogens through the production of salivaricin B, a bacteriocin. Fermenting bacteria like lactic acid bacteria (LAB) produce hydrogen...
including G. vaginalis and P. bivia), and bacteriocin-like substances, with a broader spectrum of activity than bacteriocins (e.g. a heat-resistant peptide produced...
electrical grounding specifications in the IEC 60536-2 standard Class I bacteriocin, a type of toxin produced by some bacteria Class I biosafety cabinet...
bacteriocinogenic plasmids, are bacterial plasmids that direct the synthesis of bacteriocins, bacteriocidal proteins produced by certain types of bacteria that kill...
enhancing the intestinal mucosal barrier, providing a physical barrier, bacteriocin production (resulting in reduced numbers of pathogenic and gas-producing...
effectively handle: Bacteriocins: B. fragilis intestinal isolates secrete high levels of bacteriocin proteins and are resistant to other bacteriocins secreted by...
ampicillin, cloxacillin, novobiocin, or sulfafurazole. It produces a bacteriocin-like inhibitory substance. Allen, D. A.; Austin, B.; Colwell, R. R. (1983)...
2020-10-21. LeBlanc, Jean Guy; Todorov, Svetoslav Dimitrov (2011). "Bacteriocin producing lactic acid bacteria isolated from Boza, a traditional fermented...
of enzymes. Some species produce metabolites similar to antibiotics: bacteriocins of the corynecin-linocin type, antitumor agents, etc. One of the most...
flora provide some protection from infections by their secretion of bacteriocins and hydrogen peroxide. The healthy vagina of a woman of child-bearing...
nomenclature is Alkalihalobacillus halodurans. B. halodurans produces a bacteriocin, haloduracin, that may be useful as a lantibiotic and could be produced...
bacteria, including those that produce bacteriocins can kill and inhibit pathogens. Alternatively, purified bacteriocins such as nisin can be added directly...
virulence depended on the relative potency of the antimicrobial toxins (bacteriocins) produced by the two strains involved. When only one bacterium could...
growth of bacteria causing BV by producing H2O2, lactic acid, and/or bacteriocins, and/or inhibit the adherence of Gardnerella vaginalis to the vaginal...
plasmids was understood. Col plasmids, which contain genes that code for bacteriocins, proteins that can kill other bacteria. Degradative plasmids, which enable...
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