Ataxin-3 is a protein that in humans is encoded by the ATXN3 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000066427 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021189 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Takiyama Y, Nishizawa M, Tanaka H, Kawashima S, Sakamoto H, Karube Y, Shimazaki H, Soutome M, Endo K, Ohta S (Jul 1993). "The gene for Machado-Joseph disease maps to human chromosome 14q". Nature Genetics. 4 (3): 300–4. doi:10.1038/ng0793-300. PMID 8358439. S2CID 27424416.
Ataxin-3 is a protein that in humans is encoded by the ATXN3 gene. Machado–Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant...
Ataxin is a type of nuclear protein. The class is called ataxin because mutated forms of these proteins and their corresponding genes were found to cause...
Ataxin 7 (ATXN7) is a protein of the SCA7 gene, which contains 892 amino acids with an expandable poly(Q) region close to the N-terminus. The expandable...
Ataxin-1 is a DNA-binding protein which in humans is encoded by the ATXN1 gene. Mutations in ataxin-1 cause spinocerebellar ataxia type 1, an inherited...
degradation: role of the ubiquitin system". Acta Biologica Hungarica. 42 (1–3): 3–20. PMID 1668897. Lahvic JL, Ji Y, Marin P, Zuflacht JP, Springel MW, Wosen...
diseases, which are caused when a disease-associated protein (i.e., ataxin-1, ataxin-3, etc.) contains a large number of repeats of glutamine residues, termed...
group (COO−) of the ubiquitin's glycine and the epsilon-amino group (ε-NH+ 3) of the substrate's lysine. Trypsin cleavage of a ubiquitin-conjugated substrate...
Tymoczko JL, Stryer L (2002). "3. Protein Structure and Function". Biochemistry. San Francisco: W. H. Freeman. ISBN 978-0-7167-4684-3. Selkoe DJ (December 2003)...
Parkinson's disease has been linked to this protein when there is a protein. Ataxin-3 is the protein that, in the deubiquitinating enzyme function, forms SCA...
SUMO homologue in yeast, for example, is called SMT3 (suppressor of mif two 3). Several pseudogenes have been reported for SUMO genes in the human genome...
hydrolysis. The middle domain is divided into three regions: a 3-layer α-β-α sandwich a 3-turn α-helix and irregular loops a 6-turn α-helix. The MD is also...
secretory pathway of the acinar cells". J. Cell Sci. 107 (3): 539–49. doi:10.1242/jcs.107.3.539. PMID 7911805. Mayhew M, da Silva AC, Martin J, Erdjument-Bromage...
protein in RNA metabolism?". Human Molecular Genetics. 6 (3): 497–500. doi:10.1093/hmg/6.3.497. PMID 9147655. Hahnen E, Schönling J, Rudnik-Schöneborn...
detected, although most of these are only ever expressed at very low levels (< 0.3% of the total). The full-length mRNA encoding the secreted isoform is by far...
Global Information
