Morogoro virus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis).[1] The virus is genetically closely related to Lassa virus, known to cause Lassa fever in humans. Morogoro virus, however, does not seem to infect humans.[1] Transmission of Morogoro virus between mice is assumed to occur via direct and indirect contact.[2] Infected animals pass a latent period of 7 days and subsequently shed the virus for about 30 days, after which they recover and develop lifelong antibodies.[3] Transmission may also be possible from infected mothers to offspring and through sexual contact, as this has been suggested for other arenaviruses.[4][5]
^Borremans B, Leirs H, Gryseels S, Günther S, Makundi R, de Bellocq JG (August 2011). "Presence of Mopeia virus, an African arenavirus, related to biotope and individual rodent host characteristics: implications for virus transmission". Vector Borne Zootic Dis. 11 (8): 1125–1131. doi:10.1089/vbz.2010.0010. PMID 21142956.
^Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van Houtte N, Günther S, Leirs H (29 May 2015). "Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis". Sci Rep. 5: 10445. doi:10.1038/srep10445. PMC 4448520. PMID 26022445.
^Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S (September 2014). "Lassa serology in natural populations of rodents and horizontal transmission". Vector Borne Zoonotic Dis. 14 (9): 665–674. doi:10.1089/vbz.2013.1484. PMC 4170823. PMID 25229705.
^Webb PA, Justines G, Johnson KM (1975). "Infection of wild and laboratory animals with Machupo and Latino viruses". Bull World Health Organ. 52 (4–6): 493–499. PMC 2366657. PMID 182399.
Morogorovirus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis). The virus is genetically closely related to Lassa...
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