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Ames strain information


The Ames strain is one of 89 known strains of the anthrax bacterium (Bacillus anthracis). It was isolated from a diseased 14-month-old Beefmaster heifer that died in Sarita, Texas in 1981. The strain was isolated at the Texas Veterinary Medical Diagnostic Laboratory and a sample was sent to the United States Army Medical Research Institute of Infectious Diseases (USAMRIID).[1] Researchers at USAMRIID mistakenly believed the strain came from Ames, Iowa because the return address on the package was the USDA's National Veterinary Services Laboratories in Ames and mislabeled the specimen.[2]

The Ames strain came to wide public attention during the 2001 anthrax attacks when seven letters containing it were mailed to media outlets and US Senators on September 18, 2001, and October 9, 2001.

Because of its virulence, the Ames strain is used by the United States for developing vaccines and testing their effectiveness. Use of the Ames strain started in the 1980s, after work on weaponizing the Vollum 1B strain ended and all weaponized stocks were destroyed after the end of the U.S. biological warfare program in 1969.[3]

  1. ^ Rasko DA, Worsham PL, Abshire TG, Stanley ST, Bannan JD, Wilson MR, et al. (March 2011). "Bacillus anthracis comparative genome analysis in support of the Amerithrax investigation". Proceedings of the National Academy of Sciences of the United States of America. 108 (12): 5027–32. Bibcode:2011PNAS..108.5027R. doi:10.1073/pnas.1016657108. PMC 3064363. PMID 21383169.
  2. ^ Warrick J (2002-01-29). "One Anthrax Answer: Ames Strain Not From Iowa". The Washington Post.
  3. ^ Fainaru S, Warrick J (2001-11-25). "Deadly Anthrax Strain Leaves a Muddy Trail". Washington Post.

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Ames strain

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The Ames strain is one of 89 known strains of the anthrax bacterium (Bacillus anthracis). It was isolated from a diseased 14-month-old Beefmaster heifer...

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worldwide. USAMRIID was the first bio-facility of its type to research the Ames strain of anthrax, determined through genetic analysis to be the bacterium used...

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derived from the same bacterial strain. Known as the Ames strain, it was first researched at USAMRIID. The Ames strain was subsequently distributed to...

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in the early 1970s by Bruce Ames and his group at the University of California, Berkeley. The Ames test uses several strains of the bacterium Salmonella...

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interdependence between organisms. The Salmonella Mutagenesis test (Ames test) uses multiple strains of Salmonella typhimurium that are auxotrophic to histidine...

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Patrick and Hatfill. As soon as it became known, in October 2001, that the Ames strain of anthrax had been used in the attacks, Barbara Hatch Rosenberg and...

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strain for each prokaryotic species, but different culture collections may designate a unique name for the same strain. For example, the type strain of...

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 56–57. Palmer (1996), p. xix. Schwartz (1985), p. 216. Palmer (1996), p. x. Ames, Roger T. (1991), 'The Mencian Concept of Ren Xing: Does it Mean Human Nature...

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to Ames test, but instead of reverse mutation, it checks for forward mutation that confer resistance to 8-Azaguanine in a histidine revertant strain. Escherichia...

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improved Elisabeth's standing at court, but her health suffered under the strain. As a result, she would often visit Hungary for its more relaxed environment...

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occurs (ex. death of the subject). One classical bioassay is the Ames test. A strain of Salmonella that requires histidine to grow is put on two plates...

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disappearance of the once dominant Gros Michel cultivar. A more recent strain also affects the Cavendish cultivars which commercially replaced Gros Michel...

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