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Alkene monooxygenase information


alkene monooxygenase
Identifiers
EC no.1.14.13.69
Databases
IntEnzIntEnz view
BRENDABRENDA entry
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MetaCycmetabolic pathway
PRIAMprofile
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In enzymology, an alkene monooxygenase (EC 1.14.13.69) is an enzyme that catalyzes the chemical reaction

propene + NADH + H+ + O2 1,2-epoxypropane + NAD+ + H2O

The 4 substrates of this enzyme are propene, NADH, H+, and O2, whereas its 3 products are 1,2-epoxypropane, NAD+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is alkene,NADH:oxygen oxidoreductase. This enzyme is also called alkene epoxygenase. This enzyme participates in tetrachloroethene degradation.

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Alkene monooxygenase

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In enzymology, an alkene monooxygenase (EC 1.14.13.69) is an enzyme that catalyzes the chemical reaction propene + NADH + H+ + O2 ⇌ {\displaystyle \rightleftharpoons...

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Allyl glycidyl ether

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second alkene would produce diglycidyl ether. Allyl glycidyl ether is chiral. Most routes yield a racemic mixture. Epoxidation using monooxygenase enzyme...

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Enol ether

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In organic chemistry an enol ether is an alkene with an alkoxy substituent. The general structure is R2C=CR-OR where R = H, alkyl or aryl. A common subfamily...

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Methanol

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(2003). "Mechanistic Studies on the Hydroxylation of Methane by Methane Monooxygenase". Chem. Rev. 103 (6): 2385–2420. doi:10.1021/cr950244f. PMID 12797835...

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CYP2C19

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diazepam. CYP2C19 has been annotated as (R)-limonene 6-monooxygenase and (S)-limonene 6-monooxygenase in UniProt. The gene encodes a member of the cytochrome...

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In situ bioremediation

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are less effectively degraded. Alkene degradation is dependent on the saturation of the chain with saturated alkenes being more readily degraded. Large...

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Linoleic acid

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organic compound with the formula HOOC(CH2)7CH=CHCH2CH=CH(CH2)4CH3. Both alkene groups (−CH=CH−) are cis. It is a fatty acid sometimes denoted 18:2 (n-6)...

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Flavin adenine dinucleotide

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charge-transfer complex. Cytochrome P450 type enzymes that catalyze monooxygenase (hydroxylation) reactions are dependent on the transfer of two electrons...

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PR toxin

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fused-epoxide oxygen by P450 monooxygenase gives eremofortin B. Epoxidation of the isopropenyl sidechain, again by P450 monooxygenase, and addition of the acetyl...

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Transition metal oxo complex

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C–H bonds, epoxidize olefins, and oxidize aromatic groups. Methane monooxygenase (MMO) oxidizes methane to methanol via oxygen atom transfer from an...

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Tibolone

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transformed into the corresponding estrogens by other cytochrome P450 monooxygenases. In accordance, the closely structurally related AAS trestolone...

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Psoralen

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treatment times. The photochemically reactive sites in psoralens are the alkene-like carbon-carbon double bonds in the furan ring (the five-member ring)...

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Hydrocarbonoclastic bacteria

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to the release of secondary alcohols. The n-alkanes are oxidized by monooxygenase to secondary alcohols, then to ketones and finally to fatty acids. R...

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Pyridine

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2-, 3-, and 4-hydroxypyridine, which are generated by the action of monooxygenase. In humans, pyridine is metabolized only into N-methylpyridiniumhydroxide...

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Senecionine

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may be converted back into senecionine by cytochrome P-450 (CYP450) monooxygenases. Oxidation of senecionine to its respective dehydropyrrolizidine is...

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Alkane

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correctly. By the process of cracking, alkanes can be converted to alkenes. Simple alkenes are precursors to polymers, such as polyethylene and polypropylene...

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Gas to liquids

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that oxygenate methane to methanol. The relevant enzymes are methane monooxygenases, which are found both in soluble and particulate (i.e. membrane-bound)...

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Hopanoids

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substep of the cyclization reaction, after electrons comprising the terminal alkene bond on the squalene have attacked the hopenyl carbocation to close the...

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Methane

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water even with an insufficient supply of oxygen. The enzyme methane monooxygenase produces methanol from methane, but cannot be used for industrial-scale...

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CYP2C9

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CR (December 1998). "Molecular genetics of the human cytochrome P450 monooxygenase superfamily". Xenobiotica. 28 (12): 1129–1165. doi:10.1080/004982598238868...

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CYP2C8

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attacking various long-chain polyunsaturated fatty acids at their double (i.e. alkene) bonds to form epoxide products that act as signaling agents. It metabolizes:...

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Methylobacillus flagellatus

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dichloromethane dehalogenase, or methane monooxygenase (MMO), which degrade various environmental pollutants (i.e.: alkanes, alkenes, and mono- and poly-substituted...

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Oudenone

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Aquayamycin Bulbocapnine Metirosine Oudenone DBHTooltip Dopamine beta-monooxygenase Substrates→Products: Dopamine→Norepinephrine (Noradrenaline) Inhibitors:...

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Noretynodrel

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by aromatase or possibly other cytochrome P450 enzymes, most likely monooxygenases). Due to its very short elimination half-life and its low affinities...

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CYP2C18

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cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis...

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