Substance in blood that can promote coagulation and clumping of particles
An agglutinin is a substance in the blood that causes particles to coagulate and aggregate; that is, to change from fluid-like state to a thickened-mass (solid) state.[1]
Agglutinins can be antibodies that cause antigens to aggregate by binding to the antigen-binding sites of antibodies. Agglutinins can also be any substance other than antibodies, such as sugar-binding protein lectins.
When an agglutinin is added to a uniform suspension of particles, such as bacteria or blood, in a test tube (in vitro), agglutinin binds to the agglutinin-specific structure on the particle causing the particles to aggregate and fall to the bottom, leaving a clear suspension. This phenomenon known as agglutination is of great importance in medicine, as it serves as a diagnostic tool.[2]
^"Agglutinin". NCI Dictionary of Cancer Terms. Retrieved 7 November 2017.
An agglutinin is a substance in the blood that causes particles to coagulate and aggregate; that is, to change from fluid-like state to a thickened-mass...
Cold agglutinin disease (CAD) is a rare autoimmune disease characterized by the presence of high concentrations of circulating cold sensitive antibodies...
antibodies include cold agglutinins, Donath–Landsteiner antibodies, and cryoglobulins which are the culprits of cold agglutinin disease, paroxysmal cold...
Peanut agglutinin (PNA) is plant lectin protein derived from the fruits of Arachis hypogaea. Peanut agglutinin may also be referred to as Arachis hypogaea...
Soybean agglutinins (SBA) also known as soy bean lectins (SBL) are lectins found in soybeans. It is a family of similar legume lectins. As a lectin, it...
Wheat germ agglutinin (WGA) is a lectin that protects wheat (Triticum) from insects, yeast and bacteria. An agglutinin protein, it binds to N-acetyl-D-glucosamine...
with cold agglutinin disease is painful fingers and toes with purplish discoloration associated with cold exposure. In chronic cold agglutinin disease,...
than about 370 g/L) may indicate the blood is from someone with a cold agglutinin, or there may be some other problem resulting in one or more artifactual...
breath or dyspnea, fatigue, headache, muscle weakness and pallor. In cold agglutinin disease (cold antibody type), agglutination and impaired passage of red...
specific agglutinating activity against human A-type erythrocytes. Anti-B agglutinins such as anti-BCJ and anti-BLD separated from Charybdis japonica and Lymantria...
being taken. Contrary to cold autoimmune hemolytic anemia (e.g., cold agglutinin disease and paroxysmal cold hemoglobinuria) which happens in cold temperature...
mycoplasma pneumonia, a form of atypical bacterial pneumonia related to cold agglutinin disease. M. pneumoniae is characterized by the absence of a peptidoglycan...
microscopy methods. Fluorescein-conjugated Peanut agglutinin (FITC-PNA) or Pisum sativum agglutinin (FITC-PSA) can be used to fluorescently tag the acrosome...
occurs in cold agglutinin disease, a type of autoimmune hemolytic anemia in which people produce antibodies (termed cold agglutinins) that bind to their...
infection by Mycoplasma pneumoniae, and are rarely significant except in cold agglutinin disease. Transient antibodies against i antigen are common after infectious...
Enjaymo, is a monoclonal antibody that is used to treat adults with cold agglutinin disease (CAD). It is given by intravenous infusion. Sutimlimab prevents...
for typhus fever Paul Bunnell test for infectious mononucleosis Cold agglutinin test in primary atypical pneumonia Chemically, heterophile antigens are...
of castor for divergent concentrations of ricin and ricinus communis agglutinin". Crop Science. 39 (2): 353–7. doi:10.2135/cropsci1999.0011183X003900020008x...
mononucleosis. Mononucleosis is sometimes accompanied by secondary cold agglutinin disease, an autoimmune disease in which abnormal circulating antibodies...
manner except that cells are biconcave rather than spherical. Hemorheology Agglutinin Wikimedia Commons has media related to Rouleaux. Oxford Textbook of Medicine...
notable difference between DLHA and CAD (cold agglutinin disease) is the causative agent. For cold agglutinin disease, the causative agent is constantly...
subtype H5 (disambiguation), all A type viruses containing H5 type of agglutinin Histone H5, a histone similar to Histone H1 Haplogroup H5 (mtDNA), a genetics...
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