This article is about red blood cell stacks. "Rouleaux" is a plural form for "Rouleau". For people, see Rouleau (surname). For other uses, see Rouleau.
Rouleaux formation on wet smear.
Rouleaux (singular is rouleau) are stacks or aggregations of red blood cells (RBCs) that form because of the unique discoid shape of the cells in vertebrates. The flat surface of the discoid RBCs gives them a large surface area to make contact with and stick to each other; thus forming a rouleau. They occur when the plasma protein concentration is high, and, because of them, the ESR (erythrocyte sedimentation rate) is also increased. This is a nonspecific indicator of the presence of disease.[1]
Rouleaux formation on patient vaginal swab wet smear.
Conversely, the presence of rouleaux is a cause of disease because it will restrict the flow of blood throughout the body because capillaries can only accept free-flowing singular and independent red blood cells. The aggregations, also known as "clumping," form as an allergic reaction to certain antibiotics and not necessarily because of disease.
Conditions that cause rouleaux formation include infections, multiple myeloma, Waldenström's macroglobulinemia, inflammatory and connective tissue disorders, and cancers. It also occurs in diabetes mellitus and is one of the causative factors for microvascular occlusion in diabetic retinopathy.
Acute-phase proteins, particularly fibrinogen, interact with sialic acid on the surface of RBCs to facilitate the formation of rouleaux. An increase in the ratio of RBCs to plasma volume, as seen in the setting of polycythemia and hypovolemia, decreases rouleaux formation and decreases sedimentation.
Rouleaux formation is retarded by albumin proteins.
Rouleaux formations are also adopted by spermatozoa as a means of cooperation between genetically similar gametocytes so as to improve reproductive success through enhanced motility and, therefore, fertilization capacity—e.g., the guinea pig.
Typical mammalian erythrocytes: (a) seen from surface; (b) in profile, forming rouleaux.
Rouleaux (singular is rouleau) are stacks or aggregations of red blood cells (RBCs) that form because of the unique discoid shape of the cells in vertebrates...
promote the formation of red cell clusters called rouleaux or larger structures (interconnected rouleaux, irregular clusters). As according to Stokes' law...
A Reuleaux triangle [ʁœlo] is a curved triangle with constant width, the simplest and best known curve of constant width other than the circle. It is formed...
forces or at stasis. Erythrocytes aggregate in a special way, forming rouleaux. Rouleaux are stacks of erythrocytes which form because of the unique discoid...
steel-and-yellow-gold model with a dark blue dial and Rouleaux bracelet was worn by Jerry Seinfeld. The Rouleaux bracelet was discontinued for several years and...
sometimes occur as a stack, flat side next to flat side. This is known as rouleaux formation, and it occurs more often if the levels of certain serum proteins...
that macromolecules physically crosslink adjacent red blood cells into rouleaux structures. This occurs through adsorption of macromolecules onto the red...
cylinder and brought to the laboratory in the Behring facilities. Above the rouleaux formation which contained the red blood cells, the serum was visible. The...
Wiktionary, the free dictionary. Rouleau (French for "roll" or "roller"; plural rouleaux) can refer to: For a list of people with Rouleau as a surname, see Rouleau...
Sommerrolle ("summer roll"). The French call them nem for the fried ones and rouleaux de printemps for the others, whereas in Poland, they are known as sajgonki...
another and appear like stacks of coins, it is called 'rouleaux' formation. By observation of the rouleaux, the LBA practitioners diagnose 'acid in the blood'...
their underlying disorder. Those with myeloma will typically display a rouleaux formation on a peripheral smear and a large globulin gap, indicative of...
person's plasma, a phenomenon known as rouleaux may occur when their plasma is added to the reagent cells. Rouleaux causes red blood cells to stack together...
which provides prognostic information. On peripheral blood smear, the rouleaux formation of red blood cells is commonly seen, though this is not specific...
restaurants and pubs, with some small apartment blocks. The haberdashers V.V. Rouleaux are at number 102 and The Ivy Cafe at the north end of the lane. Marylebone...
bataillon « La peau de mes roulettes pour une casquette, La peau de mes rouleaux pour un shako ! » 15e bataillon « Je fumerais bien une pipe, Mais je n’ai...
York: Robert Appleton Company. The entry cites: Léopold Victor Delisle, Rouleaux des morts du IX au XV siecle (Paris, 1866); ____, in Bibl. de l'ecole des...
quelques problèmes relatifs à la composition des peintures narratives sur rouleaux aux xiie et xiiie siècles" [The showmen, or some problems relating to the...
2010-02-27. Archived from the original on 2010-02-27. Retrieved 2021-02-21. "What Is Cold Agglutinin Disease?". WebMD. Retrieved 2021-02-21. Rouleaux...
water had decomposed the color particles. In this condition Prof. Francis Rouleaux, director of the Royal Technical College of Charlottenburg (Berlin) and...
Huillard-Breholles Examen de chartes de l'Eglise Romaine contenues dans les rouleaux de Cluny, Paris, 1865, 84 Крип’якевич І.П. Галицько-Волинське князівство...
translator of the Old Testament he published many volumes, including Les cinq rouleaux in 1970 (Song of Songs, Ruth, Lamentations, Ecclesiastes, Esther); Jona...
properties(rheology) of biological fluids. Hemodynamics Hyperviscosity syndrome Rouleaux, is a configuration that RBC aggregates take. Baskurt, OK; Hardeman M;...
and the forty Showgirls" 29 3 "Freeze!" 30 4 "Pas de printemps pour les rouleaux"/ "No Spring for the Rolls" 31 5 "22 minutes chrono"/ "22" 32 6 "Vaudou...
red blood cells to appear stacked together on the smear, which is termed rouleaux. Some parasitic diseases, such as malaria and babesiosis, can be detected...
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