Very high magnification micrograph of an acinic cell carcinoma, abbreviated AcCC. H&E stain.
Specialty
Oncology, Pulmonology
Acinic cell carcinoma of the lung is a very uncommon tumor that typically appears close to the right bronchus.[1] As of 2022, only 29 cases have been documented in the English literature[1] since Fechner et al. first described this entity in 1972.[2] Histologically similar to the major and minor salivary glands, pluripotent cells of the submucosal serous and mucous glands of the tracheobronchial tree are thought to be the source of acinic cell carcinoma of the lung. The histologic characteristics of acinic cell carcinoma of the lung are nearly identical to those of the salivary glands.[3]
^ abNibid, Lorenzo; Frasca, Luca; Sabarese, Giovanna; Righi, Daniela; Taccogna, Silvia; Crucitti, Pierfilippo; Graziano, Paolo; Perrone, Giuseppe (2022). "DOG-1 positive primary acinic cell carcinoma of the lung and investigation of molecular status". Pathologica. 114 (5): 385–390. doi:10.32074/1591-951X-786. PMC 9614299. PMID 36305026.
^RE, Fechner; BR, Bentinck; JB, Askew (1972). "Acinic cell tumor of the lung. A histologic and ultrastructural study". Cancer. 29 (2): 501–508. doi:10.1002/1097-0142(197202)29:2<501::aid-cncr2820290241>3.0.co;2-b. ISSN 0008-543X. PMID 4111143.
^Cho, Junhun; Kim, Taeeun; Han, Joungho; Kim, Kwhanmien; Kim, Tae Sung (May 2010). "Primary Acinic Cell Carcinoma of the Lung: A Case Report" (PDF). Lung Cancer. 9 (1): 20–23. doi:10.6058/jlc.2010.9.1.20. Retrieved 28 December 2023.
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