An acid hydrolase is an enzyme that works best at acidic pHs. It is commonly located in lysosomes, which are acidic on the inside. Acid hydrolases may be nucleases, proteases, glycosidases, lipases, phosphatases, sulfatases and phospholipases and make up the approximately 50 degradative enzymes of the lysosome that break apart biological matter.[1]
types of Acid Hydrolase:
-Nucleases (P1 from Penicillium citrinum, used in the food industry for taste enhancement or present in Gouda cheese)[2]
-Lipase: for example lysosomal acid lipase.
-Proteases
-Glycosidases
^Molecular Cell Biology 6ed, Lodish et al.
^Okado, N.; Hasegawa, K.; Mizuhashi, F.; Lynch, B. S.; Vo, T. D.; Roberts, A. S. (2016). "Safety evaluation of nuclease P1 from Penicillium citrinum". Food and Chemical Toxicology. 88: 21–31. doi:10.1016/j.fct.2015.12.001. PMID 26686996.
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