positive regulation of inner ear auditory receptor cell differentiation
regulation of transcription, DNA-templated
positive regulation of inner ear receptor cell differentiation
negative regulation of apoptotic process
neuron migration
auditory receptor cell fate specification
transcription, DNA-templated
nervous system development
axon guidance
multicellular organism development
central nervous system development
brain development
inner ear auditory receptor cell differentiation
inner ear morphogenesis
positive regulation of neuron differentiation
neuron differentiation
cerebral cortex development
inner ear development
positive regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
474
11921
Ensembl
ENSG00000172238
ENSMUSG00000073043
UniProt
Q92858
P48985
RefSeq (mRNA)
NM_005172
NM_007500
RefSeq (protein)
NP_005163
NP_031526
Location (UCSC)
Chr 4: 93.83 – 93.83 Mb
Chr 6: 64.71 – 64.71 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000172238 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000073043 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY (September 1996). "Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis". Human Molecular Genetics. 5 (9): 1207–16. doi:10.1093/hmg/5.9.1207. hdl:11858/00-001M-0000-0010-50D1-1. PMID 8872459.
Protein atonal homolog 1 is a protein that in humans is encoded by the ATOH1 gene. This protein belongs to the basic helix-loop-helix (BHLH) family of...
specific TF according to literature or domain structure – No motif [50] ATOH1 ENSG00000172238 bHLH Known motif – High-throughput in vitro [51] RACAGCTGYY...
intestine, tuft cells are the sole source of secreted interleukin 25 (IL-25). ATOH1 is required for tuft cell specification but not for maintenance of a mature...
Jeffery L.; Klisch, Tiemo J.; Gray, Paul A.; Zoghbi, Huda Y. (2012). "Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness...
the Israeli Jewish population, including the novel human deafness gene ATOH1". Clinical Genetics. 98 (4): 353–364. doi:10.1111/cge.13817. ISSN 0009-9163...