ABCC9 information

ABCC9
Identifiers
Aliases	ABCC9, ABC37, ATFB12, CANTU, CMD1O, SUR2, ATP binding cassette subfamily C member 9, IDMYS
External IDs	OMIM: 601439; MGI: 1352630; HomoloGene: 56521; GeneCards: ABCC9; OMA:ABCC9 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	21,942,543 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	142,648,041 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; Achilles tendon; ; left ventricle; ; apex of heart; ; right lobe of liver; ; gastric mucosa; ; stromal cell of endometrium; ; buccal mucosa cell; ; body of uterus;
	Top expressed in
	triceps brachii muscle; ; sternocleidomastoid muscle; ; temporal muscle; ; digastric muscle; ; body of femur; ; ankle; ; ascending aorta; ; myocardium of ventricle; ; soleus muscle; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; transmembrane transporter binding; transporter activity; potassium channel regulator activity; sulfonylurea receptor activity; ATPase activity; ATP binding; ATPase-coupled inorganic anion transmembrane transporter activity; potassium channel activity; ATPase-coupled transmembrane transporter activity;
Cellular component	integral component of membrane; membrane; plasma membrane; sarcomere; sarcolemma; inward rectifying potassium channel;
Biological process	potassium ion transport; defense response to virus; signal transduction; transmembrane transport; potassium ion import across plasma membrane; regulation of cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	10060
	20928
	ENSG00000069431
	ENSMUSG00000030249
	O60706; Q8N4N7
	P70170
	NM_005691; NM_020297; NM_020298; NM_001377273; NM_001377274
NM_001044720; NM_011511; NM_021041; NM_021042; NM_021043;
	NM_001310143
	NP_005682; NP_064693; NP_001364202; NP_001364203
	NP_001038185; NP_001297072; NP_035641; NP_066378; NP_066379
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-binding cassette, sub-family C member 9 (ABCC9) also known as sulfonylurea receptor 2 (SUR2) is an ATP-binding cassette transporter that in humans is encoded by the ABCC9 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000069431 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030249 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Aguilar-Bryan L, Clement JP, Gonzalez G, Kunjilwar K, Babenko A, Bryan J (January 1998). "Toward understanding the assembly and structure of KATP channels". Physiological Reviews. 78 (1): 227–245. doi:10.1152/physrev.1998.78.1.227. PMID 9457174. S2CID 11851627.
^ Bienengraeber M, Olson TM, Selivanov VA, Kathmann EC, O'Cochlain F, Gao F, et al. (April 2004). "ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating". Nature Genetics. 36 (4): 382–387. doi:10.1038/ng1329. PMC 1995438. PMID 15034580.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000069431 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030249 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9457174-5] Aguilar-Bryan L, Clement JP, Gonzalez G, Kunjilwar K, Babenko A, Bryan J (January 1998). "Toward understanding the assembly and structure of KATP channels". Physiological Reviews. 78 (1): 227–245. doi:10.1152/physrev.1998.78.1.227. PMID 9457174. S2CID 11851627.

[pmid15034580-6] Bienengraeber M, Olson TM, Selivanov VA, Kathmann EC, O'Cochlain F, Gao F, et al. (April 2004). "ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating". Nature Genetics. 36 (4): 382–387. doi:10.1038/ng1329. PMC 1995438. PMID 15034580.

ABCC9 information

and 11 Related for: ABCC9 information

ABCC9

Dilated cardiomyopathy

Sulfonylurea receptor

List of distinct cell types in the adult human body

Brugada syndrome

Sleep

Benign early repolarization

Atrial fibrillation

ABCC8

Transmembrane domain of ABC transporters

List of OMIM disorder codes