4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain.[1] 4T1 cells are epithelial and are resistant to 6-thioguanine.[1] In preclinical research, 4T1 cells have been used to study breast cancer metastasis as they can metastasize to the lung, liver, lymph nodes, brain and bone.[2][3] The cells are known to be highly aggressive in live tissues.[4]
^ abPulaski, BA; Ostrand-Rosenberg, S (May 2001). "Mouse 4T1 breast tumor model". Current Protocols in Immunology. 20 (1): Unit 20.2. doi:10.1002/0471142735.im2002s39. PMID 18432775. S2CID 205154914.
^Lelekakis, Maria; Moseley, Jane M.; Martin, T. John; Hards, Daphne; Williams, Elizabeth; Ho, Patricia; Lowen, Darren; Javni, Jeannie; Miller, Fred R.; Slavin, John; Anderson, Robin L. (1999). "A novel orthotopic model of breast cancer metastasis to bone". Clinical & Experimental Metastasis. 17 (2): 163–170. doi:10.1023/A:1006689719505. PMID 10411109. S2CID 2971601.
^Shengyu, Yang; et al. (2012). "Mouse Models for Tumor Metastasis". Rational Drug Design. Methods in Molecular Biology. Vol. 928. pp. 221–228. doi:10.1007/978-1-62703-008-3_17. ISBN 978-1-62703-007-6. PMC 3674868. PMID 22956145.
^Disch, Bryan; et al. (30 May 2014). "Development and Characterization of a Preclinical Model of Breast Cancer Lung Micrometastatic to Macrometastatic Progression". PLoS ONE. 9 (5): e98624. Bibcode:2014PLoSO...998624B. doi:10.1371/journal.pone.0098624. PMC 4039511. PMID 24878664.
4T1 is a breast cancer cell line derived from the mammary gland tissue of a mouse BALB/c strain. 4T1 cells are epithelial and are resistant to 6-thioguanine...
Spartan ER) 4S9 560 Spartan Fire, LLC incomplete vehicle (formerly Spartan ER) 4T1 Toyota car made by Toyota Motor Manufacturing Kentucky 4T3 Toyota MPV/SUV...
Theaters of Saskatchewan, Canada". "Village of Manitou Beach, SK, Sask, S0K 4T1, Saskatchewan, Tourism, Spa, Danceland, Maniotou Regional Park, Campground"...
bone DU145 human prostate carcinoma derived from metastatic site in brain 4T1 mouse mammary gland metastatic adenocarcinoma WD-PBEC human primary bronchial...
Akslen LA, et al. (2012). "Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation". BMC...
characteristics Type High speed passenger craft Tonnage GT 478 Length 40 m Beam 10.1 m Height 3.73 m Draught 1.63 m Propulsion DIES,4T1 2 Speed 34 kn...
rather than inhibited the growth of vesicular stomatitis virus in cultured 4T1 mouse breast cancer and 786-O human kidney carcinoma cells; it also reduced...
Ectopic expression of Krüppel-like factor 17 (KLF17) in highly metastatic 4T1 cells suppresses their metastatic potential without affecting primary tumor...
ElectroSscan E3 ESEM. Fungal spores in spiders web, SE image, ElectroSscan E3 ESEM. 4T1 cells line. The micrograph of mouse breast tumor cells on cultural plastic...
extra mutation in p53. Various mouse mammary carcinoma cell lines, like 4T1 and TS/A, are metastatic in syngeneic immunocompetent mice and can be used...
g/mL. The pyranose and furanose rings are in "chair" (4C1) and "twist" (4T1) conformations, respectively, unlike their conformations in saccharose. Sucrose...
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