Varicella vaccine, also known as chickenpox vaccine, is a vaccine that protects against chickenpox.[9] One dose of vaccine prevents 95% of moderate disease and 100% of severe disease.[10] Two doses of vaccine are more effective than one.[10] If given to those who are not immune within five days of exposure to chickenpox it prevents most cases of disease.[10] Vaccinating a large portion of the population also protects those who are not vaccinated.[10] It is given by injection just under the skin.[10] Another vaccine, known as zoster vaccine, is used to prevent diseases caused by the same virus – the varicella zoster virus.[11]
The World Health Organization (WHO) recommends routine vaccination only if a country can keep more than 80% of people vaccinated.[10] If only 20% to 80% of people are vaccinated it is possible that more people will get the disease at an older age and outcomes overall may worsen.[10] Either one or two doses of the vaccine is recommended.[10] In the United States two doses are recommended starting at twelve to fifteen months of age.[9] As of 2017[update], twenty-three countries recommend all non-medically exempt children receive the vaccine, nine recommend it only for high risk groups, three additional countries recommend use in only parts of the country, while other countries make no recommendation.[12] Not all countries provide the vaccine due to its cost.[13] In the United Kingdom, Varilrix, a live viral vaccine[14] is approved from the age of 12 months, but only recommended for certain at risk groups.
Minor side effects may include pain at the site of injection, fever, and rash.[9] Severe side effects are rare and occur mostly in those with poor immune function.[10] Its use in people with HIV/AIDS should be done with care.[10] It is not recommended during pregnancy; however, the few times it has been given during pregnancy no problems resulted.[9][10] The vaccine is available either by itself or along with the MMR vaccine, in a version known as the MMRV vaccine.[10] It is made from weakened virus.[9]
A live attenuated varicella vaccine, the Oka strain, was developed by Michiaki Takahashi and his colleagues in Japan in the early 1970s.[15] American vaccinologist Maurice Hilleman's team developed a chickenpox vaccine in the United States in 1981, based on the "Oka strain" of the varicella virus.[16][17][18] The chickenpox vaccine first became commercially available in 1984.[10] It is on the WHO Model List of Essential Medicines.[19][20]
^"Varicella virus vaccine (Varivax) Use During Pregnancy". Drugs.com. 6 February 2019. Retrieved 28 December 2019.
^"Varivax – Summary of Product Characteristics (SmPC)". (emc). 29 November 2018. Retrieved 28 December 2019.
^"Varilrix 10 3.3 PFU/0.5ml, powder and solvent for solution for injection – Summary of Product Characteristics (SmPC)". (emc). 20 February 2020. Retrieved 27 February 2021.
^"Varivax – varicella virus vaccine live injection, powder, lyophilized, for suspension". DailyMed. Retrieved 27 February 2021.
^Cite error: The named reference FDA Varivax was invoked but never defined (see the help page).
^Cite error: The named reference FDA Varivax archive was invoked but never defined (see the help page).
^"Varilrix". European Medicines Agency (EMA). 26 June 2020. Retrieved 27 February 2021.
^"List of nationally authorised medicinal products" (PDF). ema.europa.eu. 27 October 2022. Retrieved 23 April 2023.
^ abcde"Chickenpox (Varicella) Vaccine Safety". Centers for Disease Control and Prevention (CDC). 27 October 2015. Archived from the original on 22 December 2015. Retrieved 15 December 2015.
^ abcdefghijklm"Varicella and herpes zoster vaccines: WHO position paper, June 2014". Relevé Épidémiologique Hebdomadaire. 89 (25): 265–287. June 2014. hdl:10665/242227. PMID 24983077.
^"Herpes Zoster Vaccination". Centers for Disease Control and Prevention. 31 July 2015. Retrieved 26 October 2021.
^Wutzler P, Bonanni P, Burgess M, Gershon A, Sáfadi MA, Casabona G (August 2017). "Varicella vaccination - the global experience". Expert Review of Vaccines. 16 (8): 833–843. doi:10.1080/14760584.2017.1343669. PMC 5739310. PMID 28644696.
^Flatt A, Breuer J (September 2012). "Varicella vaccines". British Medical Bulletin. 103 (1): 115–127. doi:10.1093/bmb/lds019. PMID 22859715.
^"Varilrix".
^Gershon AA (2007). "Varicella-zoster vaccine". In Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS (eds.). Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge: Cambridge University Press. ISBN 978-0521827140. PMID 21348127.
^Cite error: The named reference Schillie_2018 was invoked but never defined (see the help page).
^Cite error: The named reference www.historyofvaccines.org was invoked but never defined (see the help page).
^Cite error: The named reference embryo.asu.edu was invoked but never defined (see the help page).
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
Varicellavaccine, also known as chickenpox vaccine, is a vaccine that protects against chickenpox. One dose of vaccine prevents 95% of moderate disease...
also known as varicella,[pronunciation?] is a highly contagious, vaccine-preventable disease caused by the initial infection with varicella zoster virus...
vaccine combines the attenuated virus MMR (measles, mumps, rubella) vaccine with the addition of the varicella (chickenpox) vaccine. The MMRV vaccine...
Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes...
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which...
measles (MR vaccine), measles and mumps vaccine (MMR vaccine) and measles, mumps and varicellavaccine (MMRV vaccine). A rubella vaccine was first licensed...
breakthrough infections in a population. The varicellavaccine is 85% effective at preventing varicella (chickenpox) infection. However, 75% of individuals...
are extremely rare. Varicellavaccine is rarely associated with complications in immunodeficient individuals, and rotavirus vaccines are moderately associated...
presented. Varicella zoster virus is not the same as herpes simplex virus, although they belong to the same family of herpesviruses. Shingles vaccines reduce...
rubella and varicella combined vaccine (MMRV vaccine) Most health insurance plans in the United States cover the cost of vaccines, and Vaccines for Children...
Vaccination in Mexico includes the use of vaccines in advancing public health. Mexico has a multi-year program for immunization of children. The immunization...
inventing the first chickenpox vaccine. He developed the "Oka" vaccine by producing v-Oka, a live-attenuated virus strain of varicella zoster virus. Born at Higashisumiyoshi-ku...
and mortality associated with measles mumps rubella and varicella." The combined MMR vaccine induces immunity less painfully than three separate injections...
might grow. The varicella cultures failed to grow, but the polio cultures were successful. This development greatly facilitated vaccine research and ultimately...
The DPT vaccine or DTP vaccine is a class of combination vaccines against three infectious diseases in humans: diphtheria, pertussis (whooping cough)...
caused by the vaccine or not. If they are, it is extremely rare. The varicellavaccine is given between 12 and 15 months of age. Varicella spreads person...
modified form of the varicella-zoster virus. The risk of virus reactivation can be prevented by the vaccine. Recombinant vaccines ausing protein, viral...
Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille...
papillomavirus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus (HPV). Available HPV vaccines protect against either...
Carolina. Out of 152 students at the school, 110 had not received the Varicellavaccine that protects against chickenpox. The United States Advisory Committee...
The rabies vaccine is a vaccine used to prevent rabies. There are several rabies vaccines available that are both safe and effective. Vaccinations must...
vaccine hesitancy. Studies have demonstrated that children of parents who refused the pertussis vaccine, varicellavaccine, and pneumococcal vaccine are...
An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules...
the postpartum period. Varicella is a herpes virus that causes chicken pox and shingles. Administration of the varicellavaccine during pregnancy is contraindicated...