Diagram of uterus with labeled origins of cancer types.
Specialty
Gynecology, oncology
Symptoms
Endometrial cancer: vaginal bleeding, pelvic pain[1] Uterine sarcoma: vaginal bleeding, mass in the vagina[2]
Types
Endometrial cancer, uterine sarcoma[3]
Risk factors
Endometrial cancer: obesity, metabolic syndrome, type 2 diabetes, tamoxifen use, unopposed estrogens, late menopause, family history of the condition[1] Uterine sarcoma: radiation therapy to the pelvis[2]
Uterine cancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus.[3] Endometrial cancer forms from the lining of the uterus, and uterine sarcoma forms from the muscles or support tissue of the uterus.[1][2] Endometrial cancer accounts for approximately 90% of all uterine cancers in the United States.[6] Symptoms of endometrial cancer include changes in vaginal bleeding or pain in the pelvis.[1] Symptoms of uterine sarcoma include unusual vaginal bleeding or a mass in the vagina.[2]
Risk factors for endometrial cancer include obesity, metabolic syndrome, type 2 diabetes, taking pills that contain estrogen without progesterone, a history of tamoxifen use, late menopause, and a family history of the condition.[7][1] Risk factors for uterine sarcoma include prior radiation therapy to the pelvis.[2] Diagnosis of endometrial cancer is typically based on an endometrial biopsy.[1] A diagnosis of uterine sarcoma may be suspected based on symptoms, a pelvic exam, and medical imaging.[2]
Endometrial cancer can often be cured while uterine sarcoma typically is harder to treat.[3] Treatment may include a combination of surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy.[1][2] Just over 80% of women survive more than 5 years following diagnosis.[8]
In 2015 about 3.8 million women were affected globally and it resulted in 90,000 deaths.[4][5] Endometrial cancer is relatively common while uterine sarcomas are rare.[3] In the United States, uterine cancers represent 3.5% of new cancer cases.[8] They most commonly occur in women between the ages of 45 and 74 with a median age of diagnosis of 63.[8]
^ abcdefgh"Endometrial Cancer Treatment". National Cancer Institute. 26 April 2018. Retrieved 3 February 2019.
^ abcdefgh"Uterine Sarcoma Treatment". National Cancer Institute. 3 October 2018. Retrieved 3 February 2019.
^ abcd"Uterine Cancer". National Cancer Institute. 1 January 1980. Retrieved 3 February 2019.
^ ab"Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. October 2016. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
^ ab"Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. October 2016. doi:10.1016/S0140-6736(16)31012-1. PMC 5388903. PMID 27733281.
^Felix AS, Brinton LA (September 2018). "Cancer Progress and Priorities: Uterine Cancer". Cancer Epidemiology, Biomarkers & Prevention. 27 (9): 985–994. doi:10.1158/1055-9965.EPI-18-0264. PMC 6504985. PMID 30181320.
^"Endometrial Cancer Risk Factors". www.cancer.org. Retrieved 2021-09-13.
^ abc"Uterine Cancer - Cancer Stat Facts". SEER. Retrieved 3 February 2019.
Uterinecancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus. Endometrial cancer forms from the...
Endometrial cancer is sometimes called "uterinecancer", although it is distinct from other forms of cancer of the uterus such as cervical cancer, uterine sarcoma...
tubes, at the uterine horns, and the rounded part above the openings to the fallopian tubes is the fundus. The connection of the uterine cavity with a...
Uterine serous carcinoma is a malignant form of serous tumor that originates in the uterus. It is an uncommon form of endometrial cancer that typically...
hormone imbalances or anovulation to malignancy (cervical cancer, vaginal cancer or uterinecancer). In young children, or elderly adults with cognitive impairment...
Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women with fibroids have no symptoms...
Gynecologic cancer is a type of cancer that affects the female reproductive system, including ovarian cancer, uterinecancer, vaginal cancer, cervical cancer, and...
other uterine conditions and no specific screening test has been developed. This presents an issue for treatment, as the cancer spreads quickly. Uterine sarcoma...
diagnosed her with uterinecancer. She had to undergo an immediate radical hysterectomy to treat the disease. Drescher was declared cancer-free and no post-operative...
The fallopian tubes, also known as uterine tubes, oviducts or salpinges (sg.: salpinx), are paired tubes in the human female body that stretch from the...
type of uterinecancer that includes leiomyosarcoma. The FDA says that it has known for some time that the morcellators could spread uterinecancer, but...
levels with survival in Indian patients with cancer of the uterine cervix". Asian Pacific Journal of Cancer Prevention. 16 (8): 3121–3123. doi:10.7314/apjcp...
and was faculty at Cornell Medical College. He first reported that uterinecancer cells could be detected in vaginal smears in 1928, but his work was...
which have a tendency over time to progress to the most common form of uterinecancer—endometrial adenocarcinoma, endometrioid type. EIN lesions have been...
Abdominal cancers, including ovarian and uterinecancers, may cause fluid buildup in the abdominal cavity. Symptoms of cancer may be nonspecific changes to the...
ego, "Maurizio D'Ancora". Sandra Ravel died in 1954, aged 44, from uterinecancer in her native Lombardy. Mysterious Mr. Parkes (1930) Those Three French...
abnormal uterine bleeding and be a sign of an underlying disorder, such as hormone imbalance, endometriosis, uterine fibroids, uterinecancer, or vaginal...
common forms and stages of cancer, do not improve the mother's survival. In a few instances, such as advanced uterinecancer, the pregnancy cannot be continued...
myometrium is the middle layer of the uterine wall, consisting mainly of uterine smooth muscle cells (also called uterine myocytes) but also of supporting...
around us". Lovelace died at the age of 36 on 27 November 1852, from uterinecancer. The illness lasted several months, in which time Annabella took command...
focuses on cancers of the female reproductive system, including ovarian cancer, uterinecancer, vaginal cancer, cervical cancer, and vulvar cancer. As specialists...
pain from the mother. Pain can come from possible lacerations, incisions, uterine contractions and sore nipples. Appropriate medications are usually administered...
first described by pathologist Gabriel Andral in 1829 in a patient with uterinecancer. Lymphangitis carcinomatosa may show the presence of Kerley B lines...
weak and ill from May 1558. In pain, possibly from ovarian cysts or uterinecancer, she died on 17 November 1558, aged 42, at St James's Palace, during...
Moorehead died of uterinecancer on April 30, 1974, in Rochester, Minnesota, aged 73. Moorehead was one of many people to have developed cancer after exposure...
uterus growing into the uterine wall, uterine polyps, underlying bleeding problems, side effects from birth control, or cancer. More than one category...
organ of the female reproductive system that connects the vagina with the uterine cavity. The human cervix has been documented anatomically since at least...
by mouth for five years for breast cancer. Serious side effects include a small increased risk of uterinecancer, stroke, vision problems, and pulmonary...
the Memorial Sloan–Kettering Cancer Center in New York City and diagnosed with uterinecancer. By this time, the cancer had spread to her ovaries. She...
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