Vaccine that prevents infection from all strains of the flu
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The Influenza virus has both hemagglutinin and neuraminidase spikes that are being used as antigen binding sites in the search for a universal vaccine.
A universal flu vaccine is a flu vaccine that is effective against all influenza strains regardless of the virus sub type, antigenic drift or antigenic shift.[1][2][3][page needed] Hence it should not require modification from year to year. As of 2021 no universal flu vaccine had been approved for general use, several were in development,[1] and one was in clinical trial.[4]
^ abNachbagauer R, Krammer F (April 2017). "Universal influenza virus vaccines and therapeutic antibodies". Clinical Microbiology and Infection. 23 (4): 222–228. doi:10.1016/j.cmi.2017.02.009. PMC 5389886. PMID 28216325.
^Khanna M, Sharma S, Kumar B, Rajput R (25 May 2014). "Protective Immunity Based on the Conserved Hemagglutinin Stalk Domain and Its Prospects for Universal Influenza Vaccine Development". BioMed Research International (Review). 2014: 546274. doi:10.1155/2014/546274. ISSN 2314-6133. PMC 4055638. PMID 24982895. 546274.
^Sherwood, Linda M (2017). Prescott's Microbiology (10th ed.). McGraw-Hill Education. ISBN 9781259281594.
^Balfour, Hannah (2 June 2021). "First-in-human universal flu vaccine trial begins". European Pharmaceutical Review. United Kingdom: Russell Publishing Ltd. The Phase I trial (NCT04896086) will assess the safety and immunogenicity of the experimental vaccine, FluMos-v1
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