National Tsing Hua University (B.S; M.S) Harvard University (Ph.D.)
Known for
Xolair anti-IgE therapy Antibody microarray
Scientific career
Fields
Immunology, Biomedicine, Biotechnology
Institutions
National Tsing Hua University Tanox, Inc. Academia Sinica Immunwork, Inc.
Doctoral advisor
Alfred L. Goldberg
Tse Wen Chang (Chinese: 張子文; pinyin: Zhāng Zǐwén, born August 25, 1947) is an immunology researcher, whose career spans across academia and industry. His early research involving the Immunoglobulin E (IgE) pathway and antibody-based therapeutics lead to the development of omalizumab (also known as Xolair), a medication that has been approved for the treatment of severe allergic asthma and severe chronic spontaneous urticaria.[1] Chang is a cofounder of Tanox, a biopharmaceutical company specialized in anti-IgE therapies for the treatment of allergic diseases.[2] After Tanox's tripartite partnership with Genentech and Novartis was forged in 1996, Chang returned to his alma mater, the National Tsing Hua University in Taiwan and served as the Dean (1996–1999) of the College of Life Sciences.[3] Chang was appointed by the Taiwanese government as President of the Development Center for Biotechnology (DCB) in 2000, and served as a Science and Technology Advisor of the Executive Yuan from 2002 to 2006.[4] From 2006 to 2016, he was tenured as Distinguished Research Fellow at the Genomics Research Center, Academia Sinica.[5] He founded Immunwork, Inc. in 2014.
^Chang, Tse Wen; Chen, Christina; Lin, Chien-Jen; Metz, Martin; Church, Martin K.; Maurer, Marcus (2015-02-01). "The potential pharmacologic mechanisms of omalizumab in patients with chronic spontaneous urticaria". Journal of Allergy and Clinical Immunology. 135 (2): 337–342.e2. doi:10.1016/j.jaci.2014.04.036. PMID 24948369. S2CID 13090739.
^"Tanox, Inc. – Company Profile, Information, Business Description, History, Background Information on Tanox, Inc". Reference for Business. Advameg, Inc. Retrieved 3 May 2017.
^"2008年：張子文校友". National Tsing Hua University. Retrieved 3 May 2017.
^"張子文 (Dr. Tse-Wen Chang)". Board of Science and Technology, Executive Yuan. Retrieved 3 May 2017.
^"Chang, Tse Wen". Genomics Research Center, Academia Sinica. Retrieved 3 May 2017.
It-hong Song Wen-chang (Chinese: 宋文城; Wen-chang SONG), Taiwanese ambassador to Kiribati; see List of ambassadors of China to Kiribati TseWenChang (born 1947;...
scientists, Nancy T. Chang and TseWenChang in March 1986 with $250,000, which was a large part of their family savings at that time. Both Changs grew up and...
illustrated in antibody microarrays (also referred to as antibody matrix) by TseWenChang in 1983 in a scientific publication and a series of patents. The "gene...
introduced by TseWenChang in 1983 in a scientific publication and a series of patents, when he was working at Centocor in Malvern, Pennsylvania. Chang coined...
name as Mao Tse-tung, using the Wade–Giles system of transliteration for Standard Chinese though with the circumflex accent in the syllable Tsê dropped....
under wraps. Hsieh Ying-xuan as Wen-fang Weng Jag Huang as Chia-ching Chen Gingle Wang as Ya-ching Chang Leon Dai as Chang-tse Chao Buffy Chen as Jung-chih...
Houston-based Tanox, started by two biomedical scientists, Nancy T. Chang and TseWenChang, in 1986. There was a legal dispute whether Tanox had the right...
wife Tony Leung Ka Fai as Chen Chang Xing Feng Tsui Fan as Grand Uncle Nikki Hsin Ying Hsieh as Jin Yuner Patrick Tse as 10th Grandmaster Daniel Wu as...
George F. Gao China 2013 Mei-Hwei Chang Taiwan 2013 Turgay Dalkara Turkey 2014 Irene Oi Lin NG China 2014 TseWenChang Taiwan 2015 Eduardo Arzt Argentina...
3rd Group Army – Sun Tongxuan 12th Army – Sun Tongxuan 20th Division – ChangTse-ming 22nd Division – Ku Liang-min 81st Division – Chan Shu-tang 55th Army...
ISBN 9783662464823. Feng, Minfei (2016). 危世圖存：中國歷史上的15次中興. 新華出版社. ISBN 9787516627617. Tse, Wicky (2018). The Collapse of China's Later Han Dynasty, 25-220 CE: The...
California Press. ISBN 9780520222366. Hummel, Arthur W. Sr., ed. (1943). "Lin Tsê-hsü" . Eminent Chinese of the Ch'ing Period. United States Government Printing...
defending Pingxingguan: [1] 17th Army - Kao Kuei-tse (from 7th Group Army) 84th Division - Kao Kuei-tse (concurrent) 21st Division - Li Hsien-chou 73rd...
Iron-Pellet Lee Chang sheng da (1955) – Cheng Nam San Tian chang di jiu (1955) Huang Fei Hong hua di qiang pao (1955) – Suen Kwan-Lun Huang Fei Hong wen zhen si...
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