Trichosanthin is a ribosome-inactivating protein.[1][2] It is derived from Trichosanthes kirilowii.[3] It is also an abortifacient.[4]
^Too PH, Ma MK, Mak AN, et al. (February 2009). "The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome". Nucleic Acids Res. 37 (2): 602–10. doi:10.1093/nar/gkn922. PMC 2632931. PMID 19073700.
^Shaw PC, Lee KM, Wong KB (May 2005). "Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties". Toxicon. 45 (6): 683–9. doi:10.1016/j.toxicon.2004.12.024. PMID 15804517.
^Zhao J, Ben LH, Wu YL, et al. (July 1999). "Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors". J. Exp. Med. 190 (1): 101–11. doi:10.1084/jem.190.1.101. PMC 2195565. PMID 10429674.
^Li MX, Yeung HW, Pan LP, Chan SI (November 1991). "Trichosanthin, a potent HIV-1 inhibitor, can cleave supercoiled DNA in vitro". Nucleic Acids Res. 19 (22): 6309–12. doi:10.1093/nar/19.22.6309. PMC 329144. PMID 1659689.
Trichosanthin is a ribosome-inactivating protein. It is derived from Trichosanthes kirilowii. It is also an abortifacient. Too PH, Ma MK, Mak AN, et al...
this may be an unnecessary extrapolation from the toxicity of purified trichosanthin. Extracts from the plant have been shown to damage the protein coat...
short time. A third treatment promoted by Woodroof, called Compound Q (Trichosanthin), was specifically linked to two deaths during trials, and therefore...
develops and beetin in created and accumulates inside the cells. Saporin Trichosanthin Iglesias, Rosario; Pérez, Yolanda; de Torre, Carlos; Ferreras, J. Miguel;...
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