cellular response to phorbol 13-acetate 12-myristate
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
6175
11837
Ensembl
ENSG00000089157
ENSMUSG00000067274
UniProt
P05388
P14869
RefSeq (mRNA)
NM_053275 NM_001002
NM_007475
RefSeq (protein)
NP_000993 NP_444505 NP_000993.1 NP_444505.1
NP_031501
Location (UCSC)
Chr 12: 120.2 – 120.2 Mb
Chr 5: 115.7 – 115.7 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
60S acidic ribosomal protein P0 is a protein that in humans is encoded by the RPLP0 gene.[5][6]
Ribosomes catalyze protein synthesis and consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000089157 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000067274 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
60SacidicribosomalproteinP0 is a protein that in humans is encoded by the RPLP0 gene. Ribosomes catalyze protein synthesis and consist of a small 40S...
60Sacidicribosomalprotein P2 is a protein that in humans is encoded by the RPLP2 gene. Ribosomes, the organelles that catalyze protein synthesis, consist...
60Sacidicribosomalprotein P1 is a protein that in humans is encoded by the RPLP1 gene. Ribosomes, the organelles that catalyze protein synthesis, consist...
A ribosomalprotein (r-protein or rProtein) is any of the proteins that, in conjunction with rRNA, make up the ribosomal subunits involved in the cellular...
60Sribosomalprotein L12 is a protein that in humans is encoded by the RPL12 gene. Ribosomes, the organelles that catalyze protein synthesis, consist...