Transmission Raman spectroscopy (TRS) is a variant of Raman spectroscopy which is advantageous in probing bulk content of diffusely scattering samples. Although it was demonstrated in the early days of Raman spectroscopy[1] it was not exploited in practical settings until much later, probably due to limitations of technology at the time. It was rediscovered in 2006,[2] where the authors showed that it was capable of allowing Raman spectroscopy through many millimetres of tabletted or powdered samples. In addition, this research has also identified several highly beneficial analytical properties of this approach, including the ability to probe bulk content of powders and tissue in the absence of subsampling and to reject Raman and fluorescence components originating from the surface of the sample.
^B. Schrader; G. Bergmann (1967). "Die Intensität des Ramanspektrums polykristalliner Substanzen". Fresenius' Z. Anal. Chem. 225 (2): 225–230. doi:10.1007/bf00983673. S2CID 94487523.
^P. Matousek; A. W. Parker (2006). "Bulk Raman Analysis of Pharmaceutical Tablets". Applied Spectroscopy. 60 (12): 1353–1357. Bibcode:2006ApSpe..60.1353M. doi:10.1366/000370206779321463. PMID 17217583. S2CID 32218439.
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Ramanspectroscopy (/ˈrɑːmən/) (named after physicist C. V. Raman) is a spectroscopic technique typically used to determine vibrational modes of molecules...
paper with Bergmann of 1967 about the first successful use of TransmissionRamanspectroscopy for chemical analysis of Organic solids, e.g. pharmaceutical...
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detection, and manipulation of light in form of photons through emission, transmission, modulation, signal processing, switching, amplification, and sensing...
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(fluorescence), (optical) transmission or scattering (Raman). A consensus currently exists that the fluorescence (emission) and Raman scattering modes are...
Correlation Method Applicable to Infrared, Raman, and Other Types of Spectroscopy". Applied Spectroscopy. 47 (9): 1329–1336. Bibcode:1993ApSpe..47.1329N...
interactions. The most common technique is tunable diode laser absorption spectroscopy (TDLAS) which has become commercialized and is used for a variety of...
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