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Transcription bubble information


A transcription bubble is a molecular structure formed during DNA transcription when a limited portion of the DNA double helix is unwound. The size of a transcription bubble ranges from 12 to 14 base pairs. A transcription bubble is formed when the RNA polymerase enzyme binds to a promoter and causes two DNA strands to detach.[1] It presents a region of unpaired DNA, where a short stretch of nucleotides are exposed on each strand of the double helix.[1][2]

Transcription bubble
A molecular structure composed of unwound and unpaired DNA, where a short stretch of nucleotides are exposed on each strand of the double helix, allowing RNA polymerase binding, and nascent RNA synthesis within this region.
  1. ^ a b Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter (2015). Wilson, John; Hunt, Tim (eds.). Molecular Biology of the Cell (6 ed.). Garland Science. pp. 306–307. doi:10.1201/9781315735368. ISBN 9781315735368.
  2. ^ Clark, David P.; Pazdernik, Nanette J. (1 January 2016), Clark, David P.; Pazdernik, Nanette J. (eds.), "Chapter 2 - DNA, RNA, and Protein", Biotechnology (Second Edition), Academic Cell, pp. 33–61, doi:10.1016/b978-0-12-385015-7.00002-8, ISBN 9780123850157, retrieved 30 September 2019

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Transcription bubble

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A transcription bubble is a molecular structure formed during DNA transcription when a limited portion of the DNA double helix is unwound. The size of...

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Coding strand

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This unwound section is known as the transcription bubble. The RNA polymerase, and with it the transcription bubble, travels along the noncoding strand...

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Eukaryotic transcription

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"Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome"....

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Transcription preinitiation complex

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one turn of DNA to unwind and form the transcription bubble. The template strand of the transcription bubble engages with the RNA polymerase II active...

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General transcription factor

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one turn of DNA to unwind and form the transcription bubble. The template strand of the transcription bubble engages with the RNA polymerase II active...

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Nucleotide excision repair

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junction between the double-stranded and single-stranded DNA around the transcription bubble. In addition to stabilizing TFIIH, XPG also has endonuclease activity;...

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Bacterial transcription

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is called the open complex. This open complex is also called the transcription bubble. Only one strand of DNA, called the template strand (also called...

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Transcription factor II H

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activities and help create the transcription bubble. In a test tube, these subunits are only required for transcription if the DNA template is not already...

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RNA polymerase II holoenzyme

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not unwind the promoter. TFIIH helps create the transcription bubble and may be required for transcription if the DNA template is not already denatured or...

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Archaeal transcription

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channels; the two DNA strands reunite at the trailing end of the transcription bubble while the single strand RNA emerges alone. A number of elongation...

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RNA polymerase

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unwound section of DNA of approximately 13 bp, referred to as the "transcription bubble". Supercoiling plays an important part in polymerase activity because...

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DSIF

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Pause Factor That Binds to the Non-template DNA within the Paused Transcription Bubble". Journal of Biological Chemistry. 291 (10): 5299–5308. doi:10.1074/jbc...

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Transcription factor II B

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nucleotides long, transcription enters the elongation phase, the beginning of which is characterised by the collapsing of the DNA bubble and the ejection...

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Words Bubble Up Like Soda Pop

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Words Bubble Up Like Soda Pop (Japanese: サイダーのように言葉が湧き上がる, Hepburn: Saidā no Yō ni Kotoba ga Wakiagaru) is a Japanese animated slice-of-life romantic comedy-drama...

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Egg waffle

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original Cantonese name, gai daan jai (雞蛋仔), and in English, an egg puff, bubble waffle, eggette, pancake balls, pancake waffle, egglet, and puffle.[citation...

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Hysteresis

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the relative magnitude of the bubble volume at the maximum capillary pressure to the dead volume in the system. The bubble shape hysteresis is a consequence...

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Transcription into Japanese

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(unlike spelling in English, for example). A much less common form of transcription, Ateji, uses kanji characters for their phonetic values. Because Japanese...

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DNA replication

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Polymerase chain reaction (PCR), ligase chain reaction (LCR), and transcription-mediated amplification (TMA) are examples. In March 2021, researchers...

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A South Sea Bubble

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South Sea Bubble at IMDb v t e v t e The below is a transcription from a ship's manifest and relates to the making of the film "A South Sea Bubble"; Vessel;...

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Samantha Womack

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World Records Limited. p. 279. ISBN 978-1-904994-10-7. "All About Soap Bubble Awards". 19 February 2012. Archived from the original on 2 April 2008. Retrieved...

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French Braille

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⠘⠑ €, ⠘⠎ $, ⠘⠇ £ It is also used in comic strips: ⠘⠻ (speech bubble), ⠘⠳ (thought bubble) The traditional system of digits is to add the number sign ⠼...

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