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Thomas Cech
Born
(1947-12-08) December 8, 1947 (age 76)
Chicago, Illinois, US
Alma mater
Grinnell College (B.A., 1970) University of California, Berkeley (Ph.D., 1975) Massachusetts Institute of Technology (Postdoctoral)
Known for
Ribozyme, Telomerase
Awards
Pfizer Award in Enzyme Chemistry (1985) Newcomb Cleveland Prize (1986) NAS Award in Molecular Biology (1987) Rosenstiel Award (1988) Nobel Prize in Chemistry (1989) National Medal of Science (1995) Othmer Gold Medal (2007)
Scientific career
Institutions
University of Colorado, Howard Hughes Medical Institute
Thesis
Characterization of the most rapidly renaturing sequences in the main band DNA of the mouse (Mus musculus)(1975)
Doctoral advisor
John E. Hearst
Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, suggesting that life might have started as RNA.[1] He found that RNA can not only transmit instructions, but also that it can speed up the necessary reactions.[2]
He also studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after they are shortened during cell division.[3]
As president of Howard Hughes Medical Institute, he promoted science education, and he teaches an undergraduate chemistry course at the University of Colorado.
^The Nobel Prize in Chemistry 1989: Illustrated Presentation
^Thomas Cech – Hyde Park Civilizace | Česká televize (in Czech), retrieved July 13, 2023
^Telomeres, Telomerase, and Other Noncoding RNAs, Howard Hughes Medical Institute, July 13, 2010
Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery...
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genetic information, leading to life as we know it. Principle of concept ThomasCech, in 2009, proposed the existence of the RNP world after his observation...
research at the University of Colorado, Boulder, under the mentorship of ThomasCech. He has been a professor with the Howard Hughes Medical Institute (HHMI)...
being the ribosome), the discovery of which earned Sidney Altman and ThomasCech the Nobel Prize in Chemistry in 1989: in the 1970s, Altman discovered...
Norman Ramsey Jr.; Hans Georg Dehmelt; Wolfgang Paul Sidney Altman; ThomasCech J. Michael Bishop; Harold E. Varmus Camilo José Cela Tenzin Gyatso (The...
Gothenburg Alexis Carrel Physiology or Medicine 1912 Rockefeller University ThomasCech Chemistry 1989 University of Colorado Boulder James Chadwick Physics...
were discovered in the early 1980s, leading to a 1989 Nobel award to ThomasCech and Sidney Altman. In 1990, it was found in Petunia that introduced genes...
ISBN 041545705X. Hager 2008, p. 235–236. Creese, Mary R. S. Creese; Creese, Thomas M. (2004). Ladies in the Laboratory II: West European women in science,...
The Czechs (Czech: Češi, pronounced [ˈtʃɛʃɪ]; singular Czech, masculine: Čech [ˈtʃɛx] , singular feminine: Češka [ˈtʃɛʃka]), or the Czech people (Český...
United States "for their discovery of catalytic properties of RNA" ThomasCech (b. 1947) United States 1990 Elias James Corey (b. 1928) United States...
process. Notable alumni include: Emily Bergl, 1997, actress and singer ThomasCech, 1970, co-winner of 1989 Nobel Prize in Chemistry, president of Howard...
Ramsey Jr., Hans Georg Dehmelt, Wolfgang Paul Chemistry – Sidney Altman, ThomasCech Medicine – J. Michael Bishop, Harold E. Varmus Literature – Camilo José...
2011 George M. Whitesides, 2010 Ahmed Zewail, 2009 Yuan Tseh Lee, 2008 Thomas R. Cech, 2007 Ronald Breslow, 2006 James D. Watson, 2005 Jon Huntsman, Sr.,...
complex, which is involved in the maturation of pre-tRNAs. In 1989, Thomas R. Cech and Sidney Altman shared the Nobel Prize in chemistry for their "discovery...
dismissals of club director Marina Granovskaia and technical advisor Petr Čech (with whom Tuchel had a strong working relationship); Tuchel was said to...
justice of the Supreme Court of the United States from 1916 to 1939 ThomasCech, a Nobel Laureate in chemistry Anton Cermak, the mayor of Chicago, Illinois...
Frances Arnold (Ph.D. 1985 Chemical Engineering) - Nobel laureate (2018) ThomasCech (Ph.D. 1975 Chemistry) - Nobel laureate (1989) Robert F. Curl, Jr. (Ph...
scientist Elena Ceaușescu (1916–1989), Romanian communist politician ThomasCech (born 1947), 1989 Nobel Prize in Chemistry Martin Chalfie (born 1947)...
Jr. 1993—Donald J. Cram, Norman Hackerman 1994—George S. Hammond 1995—ThomasCech, Isabella Karle 1996—Norman Davidson 1997—Darleane C. Hoffman, Harold...
heterolytic cleavage of H2. H2 ⇌ H+ + H− Since discovery of ribozymes by ThomasCech and Sidney Altman in the early 1980s, ribozymes have been shown to be...
– Gérard Blanc, French singer, guitarist, and actor (d. 2009) 1947 – ThomasCech, American chemist and academic, Nobel Prize laureate 1947 – Kati-Claudia...
describes part of a DNA sequence which later will be called CRISPR. 1989: ThomasCech discovered that RNA can catalyze chemical reactions, making for one of...
was discovered located in the rRNA transcript of this species: 82 by ThomasCech and his coworks.: 205 This was considered the first ribozyme that can...
determining the structure of threonine. Member Natl. Acad. Sci. USA. ThomasCech (b. 1947). American biochemist at the University of Colorado, famous...