American biochemist and Nobel laureate (born 1964)
Jennifer Doudna
ForMemRS
Doudna in 2023
Born
(1964-02-19) February 19, 1964 (age 60)
Washington, D.C., U.S.
Education
Pomona College (BA)
Harvard University (MA, PhD)
Known for
First X-ray based structure of catalytic RNA
RNA interference
CRISPR
Spouse
Jamie Cate
Awards
Alan T. Waterman Award (2000)
Jacob Heskel Gabbay Award (2014)
Breakthrough Prize in Life Sciences (2015)
Princess of Asturias Award (2015)
Tang Prize in Biopharmaceutical Science (2016)
Japan Prize (2017)
Kavli Prize in Nanoscience (2018)
Wolf Prize in Medicine (2020)
Nobel Prize in Chemistry (2020)
Full list
Scientific career
Fields
Biochemistry
CRISPR
RNA biology
Gene editing
Institutions
University of Colorado, Boulder
Yale University
University of California, Berkeley
Gladstone Institutes
University of California, San Francisco
Thesis
Towards the Design of an RNA Replicase(1989)
Doctoral advisor
Jack Szostak
Other academic advisors
Thomas Cech
Doctoral students
Rachel Haurwitz
Janice Chen
Lei Stanley Qi
Basem Al-Shayeb
Website
Doudna Lab website Hughes Institute website
Jennifer Anne DoudnaForMemRS (/ˈdaʊdnə/;[1] born February 19, 1964)[2] is an American biochemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing."[3][4] She is the Li Ka Shing Chancellor's Chair Professor in the department of chemistry and the department of molecular and cell biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997.[5]
Doudna graduated from Pomona College in 1985 and earned a Ph.D. from Harvard Medical School in 1989. Apart from her professorship at Berkeley, she is also founder and chair of the governance board of the Innovative Genomics Institute, which she co-founded in 2014.[6] Doudna is also a faculty scientist at Lawrence Berkeley National Laboratory, a senior investigator at the Gladstone Institutes, and an adjunct professor of cellular and molecular pharmacology at the University of California, San Francisco (UCSF).[7][8][9][10]
In 2012, Doudna and Emmanuelle Charpentier were the first to propose that CRISPR-Cas9 (enzymes from bacteria that control microbial immunity) could be used for programmable editing of genomes,[11][12] which has been called one of the most significant discoveries in the history of biology.[13] Since then, Doudna has been a leading figure in what is referred to as the "CRISPR revolution" for her fundamental work and leadership in developing CRISPR-mediated genome editing.[11]
Her many other awards and fellowships include the 2000 Alan T. Waterman Award for her research on the structure of a ribozyme, as determined by X-ray crystallography[14] and the 2015 Breakthrough Prize in Life Sciences for CRISPR-Cas9 genome editing technology, with Charpentier.[15] She has been a co-recipient of the Gruber Prize in Genetics (2015),[16] the Tang Prize (2016),[17] the Canada Gairdner International Award (2016),[18] and the Japan Prize (2017).[19] She was named one of the Time 100 most influential people in 2015,[20] and in 2023 was inducted into the National Inventors Hall of Fame.[21]
^"Pondering 'what it means to be human' on the frontier of gene editing". The Washington Post. May 3, 2016. Archived from the original on October 15, 2020. Retrieved October 14, 2020.
^"Jennifer Doudna – American biochemist". Encyclopædia Britannica Online. Archived from the original on October 7, 2020. Retrieved November 13, 2015.
^Wu, Katherine J.; Zimmer, Carl; Peltier, Elian (October 7, 2020). "Nobel Prize in Chemistry Awarded to 2 Scientists for Work on Genome Editing". The New York Times. Archived from the original on October 8, 2020. Retrieved October 7, 2020.
^"Press release: The Nobel Prize in Chemistry 2020". nobelprize.org. Nobel Foundation. October 7, 2020. Archived from the original on January 15, 2021. Retrieved October 7, 2020.
^"Curriculum Vitae (Jennifer A. Doudna)" (PDF). Lawrence Berkeley National Laboratory. Archived (PDF) from the original on January 15, 2017. Retrieved October 24, 2017.
^"Jennifer Doudna". Innovative Genomics Institute (IGI). Retrieved December 29, 2023.
^Multiple sources:
"UC Berkeley's Jennifer Doudna wins 2020 Nobel Prize in Chemistry". University of California, Berkeley. October 7, 2020. Archived from the original on October 7, 2020. Retrieved October 10, 2020.
Langelier, Julie (September 5, 2018). "Jennifer Doudna Opens Laboratory at the Gladstone Institutes". Gladstone Institutes. Archived from the original on October 10, 2018. Retrieved October 9, 2018.
"Interview with Jennifer Doudna (recorded in 2004)". National Academy of Sciences. Archived from the original on December 18, 2015. Retrieved November 8, 2017.
^Melissa Marino (December 1, 2004). "Biography of Jennifer A. Doudna". Proceedings of the National Academy of Sciences of the United States of America. 101 (49): 16987–16989. Bibcode:2004PNAS..10116987M. doi:10.1073/PNAS.0408147101. ISSN 0027-8424. PMC 535403. PMID 15574498. Wikidata Q34553023.
^Jennifer Doudna's publications indexed by the Scopus bibliographic database. (subscription required)
^Jennifer Doudna publications indexed by Google Scholar
^ abJennifer A. Doudna and Samuel H. Sternberg. A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution. Houghton Mifflin Harcourt, 2017.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^Pollack, Andrew (May 11, 2015). "Jennifer Doudna, a Pioneer Who Helped Simplify Genome Editing". The New York Times. Archived from the original on January 2, 2022. Retrieved May 12, 2015.
^"Alan T. Waterman Award Recipients, 1976 – present". National Science Foundation. Archived from the original on March 2, 2015. Retrieved October 31, 2017.
^"Laureates: Jennifer A. Doudna". breakthroughprize.org. Archived from the original on April 20, 2022. Retrieved October 31, 2017.
^"2015 Genetics Prize: Jennifer Doudna". The Gruber Foundation. Archived from the original on September 5, 2016. Retrieved October 24, 2017.
^"Laureates: Biopharmaceutical Science (2016)". Tang Prize Foundation. Archived from the original on November 7, 2017. Retrieved November 1, 2017.
^"Jennifer Doudna". Canada Gairdner Foundation. Archived from the original on June 12, 2018. Retrieved November 2, 2017.
^"Laureates of the Japan Prize: Jennifer A. Doudna, Ph.D." The Japan Prize Foundation. Archived from the original on November 7, 2017. Retrieved November 1, 2017.
^Cite error: The named reference Time100-2015 was invoked but never defined (see the help page).
^"2023 Inductee Jennifer Doudna | National Inventors Hall of Fame®". www.invent.org. December 28, 2023. Retrieved December 29, 2023.
Jennifer Anne Doudna ForMemRS (/ˈdaʊdnə/; born February 19, 1964) is an American biochemist who has done pioneering work in CRISPR gene editing, and made...
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technology themes forming the backdrop of the book. Molecular biologist JenniferDoudna praised the book as a "fantastic adventure across time and space, grounded...
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editing" in January 2017 organized by JenniferDoudna and William Hurlbut of Stanford University. Upon invitation from Doudna, He presented a topic on "Safety...