Tetrahydrofuranylfentanyl information

Tetrahydrofuranylfentanyl
Legal status
Legal status	BR: Class F1 (Prohibited narcotics); CA: Schedule I; DE: Anlage II (Authorized trade only, not prescriptible); UK: Class A; US: Schedule I;
Identifiers
	IUPAC name N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]oxolane-2-carboxamide;
CAS Number	2142571-01-3;
PubChem CID	137332293;
UNII	Z3UD65Z8B2;
KEGG	C22758;
Chemical and physical data
Formula	C24H30N2O2
Molar mass	378.516 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1(=CC=CC=C1)N(C(=O)C1OCCC1)C1CCN(CC1)CCC1=CC=CC=C1;
	InChI InChI=1S/C24H30N2O2/c27-24(23-12-7-19-28-23)26(21-10-5-2-6-11-21)22-14-17-25(18-15-22)16-13-20-8-3-1-4-9-20/h1-6,8-11,22-23H,7,12-19H2; Key:OHJNHKUFSKAANI-UHFFFAOYSA-N;

Tetrahydrofuranylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold online as a designer drug, first appearing in Europe in late 2016.^[1]^[2]

^ "EMCDDA–Europol Joint Report on a new psychoactive substance: N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]tetrahydrofuran-2-carboxamide (tetrahydrofuranylfentanyl; THF-F)". September 2017.
^ Kanamori T, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Iwata YT (April 2020). "Metabolism of a new synthetic opioid tetrahydrofuranylfentanyl in fresh isolated human hepatocytes: Detection and confirmation of ring-opened metabolites". Drug Testing and Analysis. 12 (4): 439–448. doi:10.1002/dta.2743. PMID 31797567. S2CID 208627099.

[1] "EMCDDA–Europol Joint Report on a new psychoactive substance: N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]tetrahydrofuran-2-carboxamide (tetrahydrofuranylfentanyl; THF-F)". September 2017.

[2] Kanamori T, Segawa H, Yamamuro T, Kuwayama K, Tsujikawa K, Iwata YT (April 2020). "Metabolism of a new synthetic opioid tetrahydrofuranylfentanyl in fresh isolated human hepatocytes: Detection and confirmation of ring-opened metabolites". Drug Testing and Analysis. 12 (4): 439–448. doi:10.1002/dta.2743. PMID 31797567. S2CID 208627099.

Tetrahydrofuranylfentanyl information

and 5 Related for: Tetrahydrofuranylfentanyl information

Tetrahydrofuranylfentanyl

Brazilian Controlled Drugs and Substances Act

C24H30N2O2

List of fentanyl analogues

List of designer drugs

Legal status


Legal status	BR: Class F1 (Prohibited narcotics) CA: Schedule I DE: Anlage II (Authorized trade only, not prescriptible) UK: Class A US: Schedule I
Identifiers
IUPAC name N-Phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]oxolane-2-carboxamide
CAS Number	2142571-01-3
PubChem CID	137332293
UNII	Z3UD65Z8B2
KEGG	C22758
Chemical and physical data
Formula	C₂₄H₃₀N₂O₂
Molar mass	378.516 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1(=CC=CC=C1)N(C(=O)C1OCCC1)C1CCN(CC1)CCC1=CC=CC=C1
InChI InChI=1S/C24H30N2O2/c27-24(23-12-7-19-28-23)26(21-10-5-2-6-11-21)22-14-17-25(18-15-22)16-13-20-8-3-1-4-9-20/h1-6,8-11,22-23H,7,12-19H2 Key:OHJNHKUFSKAANI-UHFFFAOYSA-N