Designer drugs are structural or functional analogues of controlled substances that are designed to mimic the pharmacological effects of the parent drug while avoiding detection or classification as illegal. Many of the older designer drugs (research chemicals) are structural analogues of psychoactive tryptamines or phenethylamines but there are many other chemically unrelated new psychoactive substances that can be considered part of the designer drug group.[1][2][3][4] Designer drugs can also include substances that are not psychoactive in effect, such as analogues of controlled anabolic steroids and other performance and image enhancing drugs (PIEDs), including nootropics, weight loss drugs and erectile dysfunction medications. The pharmaceutical activities of these compounds might not be predictable based strictly upon structural examination. Many of the substances have common effects while structurally different or different effects while structurally similar due to SAR paradox. As a result of no real official naming for some of these compounds, as well as regional naming, this can all lead to potentially hazardous mix ups for users.[5] The following list is not exhaustive.
^"EMCDDA–Europol 2013 Annual Report on the information exchange, risk assessment and control of new psychoactive substances (implementation of Council Decision 2005/387/JHA)". EMCDDA. July 2014. Retrieved 8 August 2014.
^"EMCDDA–Europol 2012 Annual Report on the implementation of Council Decision 2005/387/JHA (New drugs in Europe, 2012)". EMCDDA. May 2013. Retrieved 8 August 2014.
^"EMCDDA–Europol 2011 Annual Report on the (information exchange, risk assessment and control of new psychoactive substances) implementation of Council Decision 2005/387/JHA". EMCDDA. April 2012. Retrieved 8 August 2014.
^"EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA". EMCDDA. May 2011. Retrieved 8 August 2014.
^Shimizu E, Watanabe H, Kojima T, Hagiwara H, Fujisaki M, Miyatake R, et al. (January 2007). "Combined intoxication with methylone and 5-MeO-MIPT". Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31 (1): 288–291. doi:10.1016/j.pnpbp.2006.06.012. PMID 16876302. S2CID 29089303.
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parent drug while avoiding detection or classification as illegal. Many of the older designerdrugs (research chemicals) are structural analogues of psychoactive...
the use of some of these drugs may result in unexpected side effects. The development ofdesignerdrugs may be considered a subfield ofdrug design. The...
hundreds of thousands of possible drugs. Any chemical substance with biological activity may be considered a drug. This list categorises drugs alphabetically...
recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines. Chem Biol Drug Des. 2023...
The following is a listof psychedelic drugsof various chemical classes, including both naturally occurring and synthetic compounds. Serotonergic psychedelics...
Pharmaceutical drugs are often classified into drug classes—groups of related drugs that have similar chemical structures, the same mechanism of action (binding...
variety of synthetic cannabinoids are designed in an attempt to avoid legal restrictions on cannabis, making synthetic cannabinoids designerdrugs. Most...
counteract respiratory depression. Listof opioids Listofdesignerdrugs Opioid epidemic in the United States Mickey Finn (drugs) Whoonga Nedelman, Michael (13...
more general terms, however, many of these drugs are also controlled by the Medicines Act 1968, there are many other drugs which are controlled by the Medicines...
multiple drugs, or from combined drug intoxication (CDI) due to poly drug use. Poly drug use often carries more risk than use of a single drug, due to...
legitimate medical use, and those which have been sold as designerdrugs and reported to national drug control agencies such as the DEA, or transnational agencies...
which has been sold as a designerdrug, first identified in Germany in 2021. It is closely related to medically used drugs such as methadone, dipipanone...
non-psychoactive drugs, such as anabolic steroids. Many governments do not criminalize the possession of a limited quantity of certain drugs for personal...
a Class C drug by section 5 of the May 2017 amendment to The Misuse ofDrugs Act 1971 along with several other designer benzodiazepine drugs. Listof benzodiazepines...
effects, which has been sold as a designerdrug, first detected in Sweden in 2014. Pentylone is a known metabolite of dimethylpentylone.[medical citation...
for hundreds of years. The advent of novel illegal or quasi-legal designerdrugs intended as substitutes or alternatives to illegal drugs has given rise...
effects which has been sold over the internet as a designerdrug and linked to numerous cases of overdose. Etazene Etonitazene Etonitazepipne Isotonitazene...
the definition of Schedule I drugs in the USA under federal drug analogue legislation, and is specifically listed as a Schedule I drug in North Dakota...
psychoactive drug enters the user's body, it induces an intoxicating effect. Recreational drugs are commonly divided into three categories: depressants (drugs that...
Council of the European Union decisions on designerdrugs. Council of the European Union issued a set of decisions on 7 designerdrugs to make them subject...
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