Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Taxadiene (taxa-4,11-diene) is a diterpene. Taxadiene is the first committed intermediate in the synthesis of taxol.[1] Six hydroxylation reactions, and a few others, are needed to convert taxadiene to baccatin III.
Enzymatically, taxadiene is produced from geranylgeranyl pyrophosphate by taxadiene synthase. A biochemical gram-scale production of taxadiene has been reported in 2010 using genetically engineered Escherichia coli.[2]
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Taxadiene (taxa-4,11-diene) is a diterpene. Taxadiene is the first committed intermediate in the synthesis of taxol. Six hydroxylation reactions, and...
important compounds such as retinol, phytol or taxadiene. Taxanes are class of diterpenoids featuring a taxadiene core. They are produced by plants of the genus...
originally identified from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy...
intermediate known as taxadiene. Taxadiene then undergoes a series of 10 oxidations via NADPH, forming the intermediate taxadiene-5α-acetoxy-10β-ol (multiple...
is a monoterpenoid, a tropolone derivative. Humulene, a sesquiterpene. Taxadiene, a diterpene, precursor to the diterpenoid taxol, an anticancer agent...
reported in 2012 together with its conversion to the next Taxol precursor taxadiene. A multigram synthetic method was reported in 2015. GEN News Highlights...
compounds in nature Limonene, a monoterpene. Humulene, a sesquiterpene. Taxadiene, a diterpene, precursor to the diterpenoid taxol, an anticancer agent...
diterpene Sclarene, a diterpene Stemarene, a diterpene Stemodene, a diterpene Taxadiene, a taxane diterpene This set index page lists chemical structure articles...
show whether taxine B could also be used as a pharmaceutical. Taxane Taxadiene Omacetaxine Graf, Engelbert; Kirfel, Armin; Wolff, Gerd-Joachim; Breitmaier...
same accomplishment with Escherichia coli in 2000. 10-Deacetylbaccatin Taxadiene Han F, Kang LZ, Zeng XL, Ye ZW, Guo LQ, Lin JF (2014). "Bioproduction...
isolate derived from Taxus wallichiana. Taxusin can be used to synthesize taxadiene -diol and -triol derivatives via deoxygenation. Taxoid 7beta-hydroxylase...
C1–C2 bond. Ongoing research efforts are directed at the synthesis of taxadiene and taxadienone intermediates. The synthesis of related taxanes decinnamoyltaxinine...
includes copalyl diphosphate synthase (kaurene synthase A). Tpsd includes taxadiene synthase, pinene synthase, and myrcene synthase. Tpse includes ent-kaurene...
includes copalyl diphosphate synthase (kaurene synthase A). Tpsd includes taxadiene synthase, pinene synthase, and myrcene synthase. Tpse includes ent-kaurene...
FPP precursor. Examples include: Myrcene synthase, pinene synthase, and taxadiene synthase Manville, J. F.; Kriz, C. D. (1977). "Juvabione and its analogues...
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