Japanese immunologist and Nobel laureate (born 1942)
Tasuku Honjo
本庶 佑
Honjo in 2013
Born
(1942-01-27) 27 January 1942 (age 82)
Kyoto, Japan
Nationality
Japanese[1]
Education
Kyoto University (BS, MD, PhD)
Known for
Class switch recombination
IL-4, IL-5, AID
Cancer immunotherapy
PD-1
Awards
Imperial Prize (1996)
Koch Prize (2012)
Order of Culture (2013)
Tang Prize (2014)
Kyoto Prize (2016)
Alpert Prize (2017)
Nobel Prize in Physiology or Medicine (2018)
Scientific career
Fields
Molecular Immunology
Institutions
Kyoto University
Doctoral advisor
Yasutomi Nishizuka
Osamu Hayaishi
Notable students
Shizuo Akira
Tasuku Honjo (本庶 佑, Honjo Tasuku, born January 27, 1942)[2] is a Japanese physician-scientist and immunologist. He won the 2018 Nobel Prize in Physiology or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1).[3]
He is also known for his molecular identification of cytokines: IL-4 and IL-5,[4] as well as the discovery of activation-induced cytidine deaminase (AID) that is essential for class switch recombination and somatic hypermutation.[5]
He was elected as a foreign associate of the National Academy of Sciences of the United States (2001), as a member of German Academy of Natural Scientists Leopoldina (2003), and also as a member of the Japan Academy (2005).
In 2018, he was awarded the Nobel Prize in Physiology or Medicine along with James P. Allison.[6] He and Allison together had won the 2014 Tang Prize in Biopharmaceutical Science for the same achievement.[7]
^"Tasuku Honjo | Biography & PD-1 | Britannica".
^"Tasuku Honjo – Facts – 2018". NobelPrize.org. Nobel Media AB. 1 October 2018. Retrieved 5 October 2018.
^Yasumasa Ishida; Yasutoshi Agata; Keiichi Shibahara; Tasuku Honjo (November 1992). "Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death". The EMBO Journal. 11 (11): 3887–3895. doi:10.1002/J.1460-2075.1992.TB05481.X. ISSN 0261-4189. PMC 556898. PMID 1396582. Wikidata Q24293504.
^Atsushi Kumanogoh; Masato Ogata (25 March 2010). "The study of cytokines by Japanese researchers: a historical perspective". International Immunology. 22 (5): 341–345. doi:10.1093/INTIMM/DXQ022. ISSN 0953-8178. PMID 20338911. Wikidata Q34106729.
TasukuHonjo (本庶 佑, HonjoTasuku, born January 27, 1942) is a Japanese physician-scientist and immunologist. He won the 2018 Nobel Prize in Physiology...
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2018, American immunologist James P. Allison and Japanese immunologist TasukuHonjo received the Nobel Prize in Physiology or Medicine for their discovery...
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within 30–50 years. 1 October James P. Allison from the United States and TasukuHonjo from Japan win the Nobel Prize in Physiology or Medicine "for their discovery...
"The Nobel Prize in Physiology or Medicine 2018 to James P. Allison and TasukuHonjo". Archived from the original on 2018-12-24. Retrieved 2018-10-01. "FDA...
Medicine "for his discoveries of mechanisms for autophagy." Tokyo 2018 TasukuHonjo 27 January 1942 Kyoto, Japan — Physiology or Medicine "for their discovery...
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