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Synthetic MRI information


Synthetic MRI is a simulation method in Magnetic Resonance Imaging (MRI), for generating contrast weighted images based on measurement of tissue properties. The synthetic (simulated) images are generated after an MR study, from parametric maps of tissue properties. It is thereby possible to generate several contrast weightings from the same acquisition. This is different from conventional MRI, where the signal acquired from the tissue is used to generate an image directly, often generating only one contrast weighting per acquisition. The synthetic images are similar in appearance to those normally acquired with an MRI scanner.

The parametric maps can be computed from a particular MRI acquisition designed to measure the tissue parameters, known as quantification. Using the maps, which contains the measured parameters for each voxel, virtual scanner settings that correspond to those used in conventional scan are given. These settings can be echo time (TE) and repetition time (TR) for a spin-echo (SE) sequence or TE, TR and inversion time (TI) for an inversion recovery (IR, FLAIR, STIR, PSIR, FSE-IR, TIRM) sequence. Using the signal equations for different types of MR acquisitions, it is then possible to calculate what a conventional image would look like. Calculating the images based on maps and scanner settings is called synthesizing the images.

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