Swine acute diarrhea syndrome coronavirus information
Type of Alphacoronavirus affecting swine
Swine acute diarrhea syndrome coronavirus
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Pisuviricota
Class:
Pisoniviricetes
Order:
Nidovirales
Family:
Coronaviridae
Genus:
Alphacoronavirus
Subgenus:
Rhinacovirus
Virus:
Swine acute diarrhea syndrome coronavirus
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a coronavirus related to Rhinolophus bat coronavirus HKU2. It is transmitted through the feces of horseshoe bats to pigs. Piglets less than 5 days old die with a probability of up to 90%.[1]
The first outbreak appeared in 2017,[2] where it caused the death of more than 24,000 piglets on 4 farms. In 2018 and 2019, the virus re-emerged in China, but there were not large-scale losses.[2] This weak re-emergence is curious, and is reminiscent of how SARS emerged in 2003 and then disappeared.[2]
During in vitro testing, human and monkey cell lines exposed to SADS-CoV became infected, suggesting that SADS-CoV may pose a risk to human health.[2]
The SADS-CoV sampled from one of the first infected pig farms was found to be 95% genetically identical to one collected from horseshoe bats (Rhinolophus), "indicating the bat origin of the pig virus".[1]
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