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Sultiame information


Sultiame
Clinical data
Trade namesOspolot
Other namesSulthiame (AAN AU), sulthiame (USAN US)
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • AU: D
Routes of
administration
Oral
ATC code
  • N03AX03 (WHO)
Legal status
Legal status
  • AU: S4 (Prescription only)
  • UK: POM (Prescription only)
  • US: ℞-only
Pharmacokinetic data
Bioavailability100% (oral)
Protein binding29%
MetabolismHepatic secretion
Elimination half-life24 hours
ExcretionFecal (10%) and renal (90%)
Identifiers
IUPAC name
  • 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide
CAS Number
  • 61-56-3 ☒N
PubChem CID
  • 5356
DrugBank
  • DB08329 checkY
ChemSpider
  • 5163 checkY
UNII
  • I00Q766CZ2
KEGG
  • D01787 checkY
ChEMBL
  • ChEMBL328560 checkY
CompTox Dashboard (EPA)
  • DTXSID4023626 Edit this at Wikidata
ECHA InfoCard100.000.465 Edit this at Wikidata
Chemical and physical data
FormulaC10H14N2O4S2
Molar mass290.35 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • O=S2(=O)N(c1ccc(cc1)S(=O)(=O)N)CCCC2
InChI
  • InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16) checkY
  • Key:HMHVCUVYZFYAJI-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Sultiame (or sulthiame) is a sulfonamide and inhibitor of the enzyme carbonic anhydrase. It is used as an anticonvulsant.

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Sultiame

Last Update:

Sultiame (or sulthiame) is a sulfonamide and inhibitor of the enzyme carbonic anhydrase. It is used as an anticonvulsant. Sultiame was first synthesised...

Word Count : 590

List of sulfonamides

Last Update:

Hydrochlorothiazide Indapamide Mefruside Metolazone Xipamide Methazolamide Ethoxzolamide Sultiame Zonisamide Mafenide Amprenavir (HIV protease inhibitor) Darunavir (HIV...

Word Count : 260

Paresthesia

Last Update:

as venlafaxine Anticonvulsant pharmaceutical drugs, such as topiramate, sultiame, or acetazolamide Benzodiazepine withdrawal syndrome Beta alanine Dextromethorphan...

Word Count : 2510

ATC code N03

Last Update:

Aminobutyric acid N03AG04 Vigabatrin N03AG05 Progabide N03AG06 Tiagabine N03AX03 Sultiame N03AX07 Phenacemide N03AX09 Lamotrigine N03AX10 Felbamate N03AX11 Topiramate...

Word Count : 275

Carbonic anhydrase inhibitor

Last Update:

sulfur containing antiseizure drug that weakly inhibits carbonic anhydrase. Sultiame is also an example of an anticonvulsant drug of this class. At high altitude...

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Anticonvulsant

Last Update:

succinimides: Ethosuximide (1955). Phensuximide. Mesuximide. Acetazolamide (1953). Sultiame. Methazolamide. Zonisamide (2000). Lamotrigine (1990). Pheneturide. Phenacemide...

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List of compounds with carbon number 10

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C10H14N2O nikethamide 59-26-7 C10H14N2O2S methallatal 115-56-0 C10H14N2O4S2 sultiame 61-56-3 C10H14N2O5 thymidine 50-89-5 C10H14N4O2 morinamide 952-54-5 C10H14N4O3...

Word Count : 28

Rolandic epilepsy

Last Update:

antiepileptic drugs, including valproate, phenytoin, gabapentin, levetiracetam and sultiame have been found effective as well. Bedtime dosing is advised by some. Treatment...

Word Count : 2787

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