Sulfadiazine is an antibiotic.[1] Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite.[3] It is a second-line treatment for otitis media, prophylaxis of rheumatic fever, chancroid, chlamydia, and infections by Haemophilus influenzae.[1] It is also used as adjunct therapy for chloroquine-resistant malaria and several forms of bacterial meningitis.[4] It is taken by mouth.[1] Sulfadiazine is available in multiple generic tablets of 500 mg. For urinary tract infections, the usual dose is 4 to 6 grams daily in 3 to 6 divided doses.[4]
Common side effects include nausea, diarrhea, headache, fever, rash, depression, and pancreatitis.[1] It should not be used in people who have severe liver problems, kidney problems, or porphyria.[3] If used during pregnancy, it may increase the risk of kernicterus in the baby.[1] While the company that makes it does not recommend use during breastfeeding, use is believed to be safe if the baby is otherwise healthy.[2] It is in the sulfonamide class of medications.[1]
Sulfadiazine was approved for medical use in the United States in 1941.[1][5] It is on the World Health Organization's List of Essential Medicines.[6] Sulfadiazine is available as a generic medication.[1]
^ abcdefghijklm"Sulfadiazine". The American Society of Health-System Pharmacists. Archived from the original on 20 December 2016. Retrieved 8 December 2016.
^ ab"Sulfadiazine Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 20 December 2016. Retrieved 28 June 2017.
^ abWorld Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 126, 205. hdl:10665/44053. ISBN 9789241547659.
^ ab"Sulfadiazine", LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012, PMID 31643992, retrieved 2021-12-27
^"Drugs@FDA: FDA Approved Drug Products". www.accessdata.fda.gov. Retrieved 11 November 2018.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
Sulfadiazine is an antibiotic. Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis,...
Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent...
antibiotic coating on medical devices. Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections. The...
Enrofloxacin is available as a fixed-dose combination medication with silver sulfadiazine for the treatment of canine otitis externa. It is available as a generic...
is usually not needed. During pregnancy, spiramycin or pyrimethamine/sulfadiazine and folinic acid may be used for treatment. Up to half of the world's...
Pyrimethamine is typically given with folinic acid and sulfadiazine. Sulfonamides (e.g. sulfadiazine) inhibit dihydropteroate synthetase, an enzyme that...
a list of sulfonamides used in medicine. Short-acting Sulfacetamide Sulfadiazine Sulfadimidine Sulfafurazole (sulfisoxazole) Sulfisomidine (sulfaisodimidine)...
Nicarbazin Oryzalin Ponazuril Robenidine Roxarsone Salinomycin Spiramycin Sulfadiazine Sulfadimethoxine Toltrazuril Coccidiostats at the U.S. National Library...
antibiotic coating in medical devices. Wound dressings containing silver sulfadiazine or silver nanomaterials are used to treat external infections. Silver...
these functional groups. Examples include: Furosemide, a loop diuretic Sulfadiazine, an antibiotic Sulfamethoxazole, an antibiotic As a sulfonamide antibiotic...
– sulfamerazine 1944 – streptomycin, the first aminoglycoside 1947 – sulfadiazine 1948 – chlortetracycline, the first tetracycline 1949 – chloramphenicol...
Other antibiotic agents, such as azelaic acid, nitrofurazone, silver sulfadiazine, and ramoplanin have been shown to be effective against MuH strains....
often recommended, there is little evidence to support their use. Silver sulfadiazine (a type of antibiotic) is not recommended as it potentially prolongs...
with a therapy consisting of flucytosine, pentamidine, fluconazole, sulfadiazine, and azithromycin. Thioridazine or trifluoperazine was also given. Successful...
can also become resistant to artemisinin, as well as atovaquone and sulfadiazine, but is not usually MDR Antihelminthic resistance is mainly reported...
vision is affected or threatened, treatment consists of pyrimethamine, sulfadiazine, and folinic acid for 4–6 weeks. Prednisone is sometimes used to decrease...
inclusion morphology, varying extrachromosomal plasmid content, and varying sulfadiazine resistance. The family Chlamydiaceae currently includes one genus and...
Prefecture in Japan. Microbacterium lacus has the ability to degrade sulfadiazine. Parte, A.C. "Microbacterium". LPSN. "Microbacterium lacus Taxon Passport...
retinitis, in combination with the folic acid antagonists pyrimethamine and sulfadiazine. Folinic acid is also used in the treatment of cerebral folate deficiency...
reduced dressing changes, and lower treatment costs compared to silver sulfadiazine cream control. Nile tilapia skin has also been used in neovaginoplasty...
generally considered first-line therapy for PCP (not to be confused with sulfadiazine and pyrimethamine, which is first line for toxoplasmosis). However, atovaquone...
in some people currently being treated with agents such as indinavir, sulfadiazine, and triamterene. Urolithiasis refers to stones originating anywhere...
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